| Literature DB >> 31167119 |
Antonio Sica1, Augusto Bleve2, Marina Chiara Garassino3.
Abstract
The pro-tumoral diversion of macrophages remains an unresolved paradox of tumor immunology and a conceptual gap in the understanding of tumor biology. Goossens et al. (2019) identify a new level of cross-regulation by which tumors increase the membrane cholesterol efflux of macrophages to enhance their pro-tumoral activation in response to IL-4.Entities:
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Year: 2019 PMID： 31167119 DOI： 10.1016/j.cmet.2019.05.011
Source DB: PubMed Journal: Cell Metab ISSN： 1550-4131 Impact factor: 27.287