Literature DB >> 31165685

Skeletal Muscle Atrophy: Discovery of Mechanisms and Potential Therapies.

Scott M Ebert1,2, Asma Al-Zougbi1, Sue C Bodine1,2, Christopher M Adams1,2,3.   

Abstract

Skeletal muscle atrophy proceeds through a complex molecular signaling network that is just beginning to be understood. Here, we discuss examples of recently identified molecular mechanisms of muscle atrophy and how they highlight an immense need and opportunity for focused biochemical investigations and further unbiased discovery work.

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Year:  2019        PMID： 31165685      PMCID： PMC6863373          DOI： 10.1152/physiol.00003.2019

Source DB:  PubMed          Journal:  Physiology (Bethesda)        ISSN： 1548-9221


  52 in total

1.  Myostatin inhibition induces muscle fibre hypertrophy prior to satellite cell activation.

Authors:  Qian Wang; Alexandra C McPherron
Journal:  J Physiol       Date:  2012-03-05       Impact factor: 5.182

2.  Trypanocidal activity and acute toxicity assessment of triterpene acids.

Authors:  Daniele da Silva Ferreira; Viviane Rodrigues Esperandim; Miriam Paula Alonso Toldo; Juliana Saraiva; Wilson Roberto Cunha; Sérgio de Albuquerque
Journal:  Parasitol Res       Date:  2010-02-06       Impact factor: 2.289

3.  The transcription factor ATF4 promotes skeletal myofiber atrophy during fasting.

Authors:  Scott M Ebert; Alex Mas Monteys; Daniel K Fox; Kale S Bongers; Bridget E Shields; Sharon E Malmberg; Beverly L Davidson; Manish Suneja; Christopher M Adams
Journal:  Mol Endocrinol       Date:  2010-03-02

4.  Gene profiling of skeletal muscle in an amyotrophic lateral sclerosis mouse model.

Authors:  Jose-Luis Gonzalez de Aguilar; Christa Niederhauser-Wiederkehr; Benoît Halter; Marc De Tapia; Franck Di Scala; Philippe Demougin; Luc Dupuis; Michael Primig; Vincent Meininger; Jean-Philippe Loeffler
Journal:  Physiol Genomics       Date:  2007-11-13       Impact factor: 3.107

5.  FOXO signaling is required for disuse muscle atrophy and is directly regulated by Hsp70.

Authors:  Sarah M Senf; Stephen L Dodd; Andrew R Judge
Journal:  Am J Physiol Cell Physiol       Date:  2009-10-28       Impact factor: 4.249

6.  Skeletal muscle denervation causes skeletal muscle atrophy through a pathway that involves both Gadd45a and HDAC4.

Authors:  Kale S Bongers; Daniel K Fox; Scott M Ebert; Steven D Kunkel; Michael C Dyle; Steven A Bullard; Jason M Dierdorff; Christopher M Adams
Journal:  Am J Physiol Endocrinol Metab       Date:  2013-08-13       Impact factor: 4.310

7.  Regulation of skeletal muscle growth by the IGF1-Akt/PKB pathway: insights from genetic models.

Authors:  Stefano Schiaffino; Cristina Mammucari
Journal:  Skelet Muscle       Date:  2011-01-24       Impact factor: 4.912

8.  Gadd45a Protein Promotes Skeletal Muscle Atrophy by Forming a Complex with the Protein Kinase MEKK4.

Authors:  Steven A Bullard; Seongjin Seo; Birgit Schilling; Michael C Dyle; Jason M Dierdorff; Scott M Ebert; Austin D DeLau; Bradford W Gibson; Christopher M Adams
Journal:  J Biol Chem       Date:  2016-06-29       Impact factor: 5.157

Review 9.  The integrated stress response.

Authors:  Karolina Pakos-Zebrucka; Izabela Koryga; Katarzyna Mnich; Mila Ljujic; Afshin Samali; Adrienne M Gorman
Journal:  EMBO Rep       Date:  2016-09-14       Impact factor: 8.807

10.  Myostatin blockade with a fully human monoclonal antibody induces muscle hypertrophy and reverses muscle atrophy in young and aged mice.

Authors:  Esther Latres; Jeffrey Pangilinan; Lawrence Miloscio; Roy Bauerlein; Erqian Na; Terra B Potocky; Ying Huang; Mark Eckersdorff; Ashique Rafique; Jason Mastaitis; Calvin Lin; Andrew J Murphy; George D Yancopoulos; Jesper Gromada; Trevor Stitt
Journal:  Skelet Muscle       Date:  2015-10-09       Impact factor: 4.912
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  24 in total

1.  An investigation of p53 in skeletal muscle aging.

Authors:  Scott M Ebert; Jason M Dierdorff; David K Meyerholz; Steven A Bullard; Asma Al-Zougbi; Austin D DeLau; Kristin C Tomcheck; Zachary P Skopec; George R Marcotte; Sue C Bodine; Christopher M Adams
Journal:  J Appl Physiol (1985)       Date:  2019-08-29

Review 2.  Edward F. Adolph Distinguished Lecture. Skeletal muscle atrophy: Multiple pathways leading to a common outcome.

Authors:  Sue C Bodine
Journal:  J Appl Physiol (1985)       Date:  2020-07-09

3.  Essential amino acid supplementation alters the p53 transcriptional response and cytokine gene expression following total knee arthroplasty.

Authors:  Jonathan B Muyskens; Ari Winbush; Douglas M Foote; Douglas W Turnbull; Hans C Dreyer
Journal:  J Appl Physiol (1985)       Date:  2020-09-03

4.  Integration of proteomic and genetic approaches to assess developmental muscle atrophy.

Authors:  David S Brooks; Kumar Vishal; Simranjot Bawa; Adrienne Alder; Erika R Geisbrecht
Journal:  J Exp Biol       Date:  2021-11-05       Impact factor: 3.312

Review 5.  CORP: Gene delivery into murine skeletal muscle using in vivo electroporation.

Authors:  David C Hughes; Justin P Hardee; David S Waddell; Craig A Goodman
Journal:  J Appl Physiol (1985)       Date:  2022-05-05

6.  Global alternative splicing landscape of skeletal muscle atrophy induced by hindlimb unloading.

Authors:  Junjie Sun; Hua Yang; Xiaoming Yang; Xin Chen; Hua Xu; Yuntian Shen; Fei Ding; Xiaosong Gu; Jianwei Zhu; Hualin Sun
Journal:  Ann Transl Med       Date:  2021-04

Review 7.  Biology of Activating Transcription Factor 4 (ATF4) and Its Role in Skeletal Muscle Atrophy.

Authors:  Scott M Ebert; Blake B Rasmussen; Andrew R Judge; Sarah M Judge; Lars Larsson; Ronald C Wek; Tracy G Anthony; George R Marcotte; Matthew J Miller; Mark A Yorek; Adrian Vella; Elena Volpi; Jennifer I Stern; Matthew D Strub; Zachary Ryan; John J Talley; Christopher M Adams
Journal:  J Nutr       Date:  2022-04-01       Impact factor: 4.798

Review 8.  Nutraceuticals in the Prevention and Treatment of the Muscle Atrophy.

Authors:  Yanan Wang; Qing Liu; Helong Quan; Seong-Gook Kang; Kunlun Huang; Tao Tong
Journal:  Nutrients       Date:  2021-06-02       Impact factor: 5.717

9.  Activating transcription factor 4 (ATF4) promotes skeletal muscle atrophy by forming a heterodimer with the transcriptional regulator C/EBPβ.

Authors:  Scott M Ebert; Steven A Bullard; Nathan Basisty; George R Marcotte; Zachary P Skopec; Jason M Dierdorff; Asma Al-Zougbi; Kristin C Tomcheck; Austin D DeLau; Jacob A Rathmacher; Sue C Bodine; Birgit Schilling; Christopher M Adams
Journal:  J Biol Chem       Date:  2020-01-17       Impact factor: 5.157

Review 10.  Muscular Atrophy and Sarcopenia in the Elderly: Is There a Role for Creatine Supplementation?

Authors:  Eimear Dolan; Guilherme G Artioli; Rosa Maria R Pereira; Bruno Gualano
Journal:  Biomolecules       Date:  2019-10-23
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