Literature DB >> 311649

Uptake of catecholamines by human cardiac muscle in vitro.

M C Petch, W G Nayler.   

Abstract

Noradrenaline uptake was studied using heart muscle from 102 patients undergoing cardiac surgery. Slices of right atrium were incubated in Krebs-Henseleit solution containing 1.3 x 10(-7) M 3H-noradrenaline. Uptake was lower in failing heart muscle and was inhibited not only by increasing the noradrenaline concentration in the incubating medium but also by adding the drugs desmethylimipramine, amitryptyline, and ouabain.

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Year:  1979        PMID: 311649      PMCID: PMC482036          DOI: 10.1136/hrt.41.3.336

Source DB:  PubMed          Journal:  Br Heart J        ISSN: 0007-0769


  6 in total

Review 1.  Catecholamine uptake processes.

Authors:  L L Iversen
Journal:  Br Med Bull       Date:  1973-05       Impact factor: 4.291

2.  Norepinephrine metabolism in hypertrophied rat hearts.

Authors:  J E Fischer; W D Horst; I J Kopin
Journal:  Nature       Date:  1965-08-28       Impact factor: 49.962

3.  Mechanism of myocardial catecholamine depletion in cardiac hypertrophy and failure in rabbits.

Authors:  H Sassa
Journal:  Jpn Circ J       Date:  1971-04

4.  Mechanism of norepinephrine depletion in experimental heart failure produced by aortic constriction in the guinea pig.

Authors:  J F Spann; C A Chidsey; P E Pool; E Braunwald
Journal:  Circ Res       Date:  1965-10       Impact factor: 17.367

5.  Concentration of catecholamines in human cardiac muscle.

Authors:  M C Petch; W G Nayler
Journal:  Br Heart J       Date:  1979-03

6.  THE UPTAKE OF NORADRENALINE BY THE ISOLATED PERFUSED RAT HEART.

Authors:  L L IVERSEN
Journal:  Br J Pharmacol Chemother       Date:  1963-12
  6 in total
  14 in total

1.  Impaired cardiac adrenergic innervation assessed by MIBG imaging as a predictor of treatment response in childhood dilated cardiomyopathy.

Authors:  P Acar; P Merlet; L Iserin; D Bonnet; D Sidi; A Syrota; J Kachaner
Journal:  Heart       Date:  2001-06       Impact factor: 5.994

2.  Chamber-specific alterations of noradrenaline uptake (uptake(1)) in right ventricles of monocrotaline-treated rats.

Authors:  K Leineweber; T Seyfarth; O E Brodde
Journal:  Br J Pharmacol       Date:  2000-12       Impact factor: 8.739

3.  Increased myocardial [123I]-metaiodobenzylguanidine uptake after enalapril treatment in patients with chronic heart failure.

Authors:  G A Somsen; B van Vlies; P A de Milliano; J J Borm; E A van Royen; E Endert; K I Lie
Journal:  Heart       Date:  1996-09       Impact factor: 5.994

4.  Neuronal dysfunction in heart failure assessed by cardiac 123-iodine metaiodobenzylguanidine scintigraphy.

Authors:  G A Somsen; E E van der Wall; B van Vlies; J J Borm; E A van Royen
Journal:  Int J Card Imaging       Date:  1996-12

5.  Decreased adrenergic neuronal uptake activity in experimental right heart failure. A chamber-specific contributor to beta-adrenoceptor downregulation.

Authors:  C S Liang; T H Fan; J T Sullebarger; S Sakamoto
Journal:  J Clin Invest       Date:  1989-10       Impact factor: 14.808

6.  Tracer norepinephrine kinetics in coronary circulation of patients with heart failure secondary to chronic pressure and volume overload.

Authors:  C P Rose; J H Burgess; D Cousineau
Journal:  J Clin Invest       Date:  1985-11       Impact factor: 14.808

7.  Prognostic value of sympathetic innervation and cardiac asynchrony in dilated cardiomyopathy.

Authors:  Alain Manrique; Mathieu Bernard; Anne Hitzel; Fabrice Bauer; Jean-François Ménard; Rémi Sabatier; Arnold Jacobson; Pierre Véra; Denis Agostini
Journal:  Eur J Nucl Med Mol Imaging       Date:  2008-08-06       Impact factor: 9.236

8.  Down-regulated beta-adrenoceptors in severely failing human ventricles: uniform regional distribution, but no increased internalization.

Authors:  H F Pitschner; A Droege; M Mitze; M Schlepper; O E Brodde
Journal:  Basic Res Cardiol       Date:  1993 Mar-Apr       Impact factor: 17.165

9.  Concentration of catecholamines in human cardiac muscle.

Authors:  M C Petch; W G Nayler
Journal:  Br Heart J       Date:  1979-03

10.  Sympathetic activity in idiopathic dilated cardiomyopathy. Influence of captopril and hydralazine.

Authors:  J Schofer; W Bleifeld
Journal:  Cardiovasc Drugs Ther       Date:  1987-08       Impact factor: 3.727

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