Literature DB >> 31164510

[A Case of Long-Term Survival Following Two-Stage Surgery for Perforated Advanced Gastric Cancer Caused by Chemotherapy].

Koki Kamiyama1, Shigeaki Sawada, Takuma Fukuda, Tetsuji Yamaguchi, Natsuki Kato, Atsuo Kojima, Koji Hino, Iwao Yamashita, Go Ogura, Hideyuki Uotani.   

Abstract

A 74-year-old man with bloody vomit was diagnosed as having clinical Stage Ⅳ advanced gastric cancer with lymph node metastasis around the abdominal aorta. Initially, for curative surgery, he was administered neoadjuvant chemotherapy. On day 32, in the second course of chemotherapy containing S-1 after 12 courses of chemotherapy containing S-1 and cisplatin, he developed pan-peritonitis owing to the perforation of gastric cancer caused by chemotherapy, and thus, we performed emergency omental implantation and peritoneal drainage. He was discharged from the hospital after 14 days with no trouble. His gastric cancer was judged to be resectable without retaining metastatic lymph nodes based on intraoperative findings and abdominal computed tomography. Therefore, 3 months after the emergency surgery, he underwent total gastrectomy with D1+(+No. 11d)lymphadenectomy. The postoperative course was uneventful. He rejected adjuvant chemotherapy despite our recommendation. Regrettably, intraabdominal dissemination was observed 15 months after total gastrectomy, and he then received chemotherapy again. He has remained alive for 57 months after the first visit to our hospital.

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Year:  2019        PMID: 31164510

Source DB:  PubMed          Journal:  Gan To Kagaku Ryoho        ISSN: 0385-0684


  2 in total

1.  Loss of DAB2IP Contributes to Cell Proliferation and Cisplatin Resistance in Gastric Cancer.

Authors:  Guannan Wang; Xu Wang; Meng Han; Xiaoming Wang
Journal:  Onco Targets Ther       Date:  2021-02-11       Impact factor: 4.147

2.  ERas Enhances Resistance to Cisplatin-Induced Apoptosis by Suppressing Autophagy in Gastric Cancer Cell.

Authors:  Huajian Tian; Wenjun Wang; Xiao Meng; Miaomiao Wang; Junyang Tan; Wenjuan Jia; Peining Li; Jianshuang Li; Qinghua Zhou
Journal:  Front Cell Dev Biol       Date:  2020-01-21
  2 in total

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