[The Role of Core Hospitals and Cooperative Hospitals for Cancer Genomic Medicine in Japan].

Genomic profiling tests using next-generation sequencer have been approved in December 2018 and their reimbursement by the national health insurance system will start soon. The Ministry of Health, Labor and Welfare assigned "Core Hospitals" and "Cooperative Hospitals" as a framework to provide cancer genomic medicine in Japan. Core Hospitals perform molecular tumor board meetings, called "Expert Panel", to make therapeutic recommendation based on the profiling results in cooperation with "Cooperate Hospitals". National Cancer Center has developed an original genomic profiling system(NCC Oncopanel system)to identify genetic alterations of 114 cancer-related genes. Clinical utility and feasibility of this system is being validated by 50Core and Cooperative Hospitals within the Advanced Medical Care B system.