| Literature DB >> 31163475 |
Donata Lissner1, Britta Siegmund1.
Abstract
Patients with ulcerative colitis and Crohn's colitis, especially in the presence of primary sclerosing cholangitis, have an increased risk of developing colorectal cancer due to the longstanding colonic inflammation. Therefore, anti-inflammatory drugs reduce this elevated risk.On the other hand, immunosuppressive medication can have direct mutagen effects or can lead to compromised tumor surveillance, therefore increasing the risk of extra-intestinal tumors. This article reviews recommendations concerning cancer surveillance strategies in patients with inflammatory bowel diseases. © Georg Thieme Verlag KG Stuttgart · New York.Entities:
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Year: 2019 PMID: 31163475 DOI: 10.1055/a-0649-5491
Source DB: PubMed Journal: Dtsch Med Wochenschr ISSN: 0012-0472 Impact factor: 0.628