Literature DB >> 31163475

[Cancer Surveillance in Inflammatory Bowel Diseases].

Donata Lissner1, Britta Siegmund1.   

Abstract

Patients with ulcerative colitis and Crohn's colitis, especially in the presence of primary sclerosing cholangitis, have an increased risk of developing colorectal cancer due to the longstanding colonic inflammation. Therefore, anti-inflammatory drugs reduce this elevated risk.On the other hand, immunosuppressive medication can have direct mutagen effects or can lead to compromised tumor surveillance, therefore increasing the risk of extra-intestinal tumors. This article reviews recommendations concerning cancer surveillance strategies in patients with inflammatory bowel diseases. © Georg Thieme Verlag KG Stuttgart · New York.

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Year:  2019        PMID: 31163475     DOI: 10.1055/a-0649-5491

Source DB:  PubMed          Journal:  Dtsch Med Wochenschr        ISSN: 0012-0472            Impact factor:   0.628


  1 in total

1.  HLJ2 Effectively Ameliorates Colitis-Associated Cancer via Inhibition of NF-κB and Epithelial-Mesenchymal Transition.

Authors:  Huachen Song; Xiaonan Tang; Xiang Li; Yufei Wang; Anjun Deng; Wenjie Wang; Haijing Zhang; Hailin Qin; LianQiu Wu
Journal:  Drug Des Devel Ther       Date:  2020-10-15       Impact factor: 4.162

  1 in total

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