[The 2018 Update of the Recommendations of the Paul-Ehrlich-Society for Chemotherapy on the Initial Parenteral Therapy of Bacterial Diseases in Adults - What's relevant for Intensive Care?]

In 2018, the PEG-recommendations for calculated initial parenteral treatment of bacterial diseases in adults were updated to a consensus-based S2k-guideline.This summary of guidelines deals with the classification of new antibiotic substances such as cephalosporin/betalactamase inhibitor combinations and MRSA-effective cephalosporines and with a need for further therapeutic drug monitoring.Due to their influence as major disease entities in intensive care, we also outline core issues regarding respiratory infections and sepsis. With this update, latest recommendations on a high scientific level are available for intensive care units and - if applied consistently - might improve the chances of critically ill patients. © Georg Thieme Verlag KG Stuttgart · New York.