| Literature DB >> 31162488 |
Michal Konrad Zarobkiewicz1, Wioleta Kowalska1, Miroslaw Slawinski2, Jacek Rolinski1, Agnieszka Bojarska-Junak1.
Abstract
The aim of this paper was to summarise knowledge of IL-22 involvement in multiple sclerosis (MS) and the possible link between IL-22 and two transcription factors - AHR and c-Maf. The conclusion is that despite numerous studies, the exact role of IL-22 in the pathogenesis of MS is still unknown. The expression and function of c-Maf in MS have not been studied. It seems that the functions of c-Maf and AHR are at least partly connected with IL-22, as both directly or indirectly influence the regulation of IL-22 expression. This possible connection has never been studied in MS.Entities:
Keywords: AHR; EAE; IL-22; c-Maf; multiple sclerosis; transcription factors
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Year: 2019 PMID： 31162488 DOI： 10.5507/bp.2019.024
Source DB: PubMed Journal: Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub ISSN： 1213-8118 Impact factor: 1.245