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Literature DB >> 31161994

Cardiovascular and Renal Outcomes of Incretin-based Therapies: A Review of Recent Clinical Trials.

Georgios Kyriakos¹, Lourdes V Quiles-Sanchez², Anna Garmpi³, Paraskevi Farmaki⁴, Konstantina Kyre⁵, Spyridon Gkogkos⁶, Spyridon Savvanis⁷, Eleni Memi⁸.

Abstract

BACKGROUND: To report the cardiovascular and renal effects of incretin-based therapies.
METHODS: The studies of clinical trials on incretin-based therapy published in medical journals from the years 2010 to 2017 were comprehensively searched using MEDLINE and EMBASE with no language restriction. The studies were reviewed and the cardiovascular and renal risks reported were recorded.
RESULTS: Incretin-based therapeutics represent novel and promising anti-diabetes drugs, the direct cardiovascular actions which may translate into demonstrable clinical benefits on cardiovascular outcomes. Furthermore, incretin-based therapies do not adversely affect renal function. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Entities: Disease

Keywords: Incretin-based therapies; cardiovascular; clinical trials; diabetes; hormones; renal

Year: 2020 PMID： 31161994 DOI： 10.2174/1573403X15666190603111056

Source DB: PubMed Journal: Curr Cardiol Rev ISSN： 1573-403X

2 in total

1. Diabetes Mellitus: An Update.

Authors: E Diamantis
Journal: Curr Cardiol Rev Date: 2020

Review 2. Experimental Agents for the Treatment of Atherosclerosis: New Directions.

Authors: Errika Voutyritsa; Georgios Kyriakos; Alexandros Patsouras; Christos Damaskos; Anna Garmpi; Evangelos Diamantis; Nikolaos Garmpis; Spyridon Savvanis
Journal: J Exp Pharmacol Date: 2021-02-18

2 in total