Literature DB >> 3116087

Production of cytotoxic factor for oligodendrocytes by stimulated astrocytes.

D S Robbins1, Y Shirazi, B E Drysdale, A Lieberman, H S Shin, M L Shin.   

Abstract

Stimulation of rat astrocytes in vitro by calcium ionophore A23187 and/or lipopolysaccharide results in the generation of a cytotoxic factor that is functionally similar to the previously described macrophage-derived cytotoxic factor, tumor necrosis factor. Like the macrophage product, the astrocyte cytotoxic factor kills murine L 929 cell targets. In addition, it kills rat oligodendrocytes, the myelin-producing cells of the central nervous system. Human recombinant tumor necrosis factor also has cytotoxic activity directed against rat oligodendrocytes.

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Year:  1987        PMID： 3116087

Source DB:  PubMed          Journal:  J Immunol        ISSN： 0022-1767            Impact factor:   5.422


  77 in total

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2.  Induction of oligodendrocyte apoptosis by C2-ceramide.

Authors:  J N Larocca; M Farooq; W T Norton
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3.  Induction of calcium-independent nitric oxide synthase activity in primary rat glial cultures.

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4.  Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions.

Authors:  K Selmaj; C S Raine; B Cannella; C F Brosnan
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5.  Regulation of neuronal excitability by release of proteins from glial cells.

Authors:  Birte A Igelhorst; Vanessa Niederkinkhaus; Claudia Karus; Maren D Lange; Irmgard D Dietzel
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2015-07-05       Impact factor: 6.237

6.  Tumor necrosis factor inhibits K+ current expression in cultured oligodendrocytes.

Authors:  B Soliven; S Szuchet; D J Nelson
Journal:  J Membr Biol       Date:  1991-11       Impact factor: 1.843

7.  Inflammation and oxidative stress induced by cigarette smoke in Lewis rat brains.

Authors:  A Khanna; M Guo; M Mehra; W Royal
Journal:  J Neuroimmunol       Date:  2012-09-30       Impact factor: 3.478

8.  Spontaneous inflammatory demyelinating disease in transgenic mice showing central nervous system-specific expression of tumor necrosis factor alpha.

Authors:  L Probert; K Akassoglou; M Pasparakis; G Kontogeorgos; G Kollias
Journal:  Proc Natl Acad Sci U S A       Date:  1995-11-21       Impact factor: 11.205

9.  Hydrogen Sulfide Protects Hippocampal Neurons Against Methamphetamine Neurotoxicity Via Inhibition of Apoptosis and Neuroinflammation.

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Journal:  J Mol Neurosci       Date:  2018-11-19       Impact factor: 3.444

10.  Cytokine-induced meningitis is dramatically attenuated in mice deficient in endothelial selectins.

Authors:  T Tang; P S Frenette; R O Hynes; D D Wagner; T N Mayadas
Journal:  J Clin Invest       Date:  1996-06-01       Impact factor: 14.808
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