Literature DB >> 31159970

Editorial Commentary: Considering Clinical Application of Bone Marrow Aspirate Concentrate for Restoration of Cartilage Defects in the Knee? Is It a Kind of Stem Cell Therapy?

Chul-Won Ha1, Yong-Beom Park2.   

Abstract

The role of bone marrow aspirate concentrate (BMAC) is still inconclusive for restoration of chondral defects in lesions of the knee. More investigation is needed; thus, clinical application of BMAC for chondral defects should be considered cautiously. Correct nomenclature of the entity of cells used in various stem cell therapies for the treatment of cartilage lesions is critical to properly assess the efficacy and safety of various stem cell therapies. Constant effort is needed to prove the therapeutic potential of various novel therapeutic options such as BMAC or stem cell therapy under correct terminology for cartilage restoration before routine clinical application.
Copyright © 2019. Published by Elsevier Inc.

Entities:  

Year:  2019        PMID: 31159970     DOI: 10.1016/j.arthro.2019.03.008

Source DB:  PubMed          Journal:  Arthroscopy        ISSN: 0749-8063            Impact factor:   4.772


  2 in total

1.  Sheep condyle model evaluation of bone marrow cell concentrate combined with a scaffold for repair of large osteochondral defects.

Authors:  Maryam Tamaddon; Gordon Blunn; Wei Xu; Maria Elena Alemán Domínguez; Mario Monzón; James Donaldson; John Skinner; Timothy R Arnett; Ling Wang; Chaozong Liu
Journal:  Bone Joint Res       Date:  2021-10       Impact factor: 5.853

Review 2.  Potential Mechanism of Action of Current Point-of-Care Autologous Therapy Treatments for Osteoarthritis of the Knee-A Narrative Review.

Authors:  Jennifer Woodell-May; Kathleen Steckbeck; William King
Journal:  Int J Mol Sci       Date:  2021-03-08       Impact factor: 5.923

  2 in total

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