| Literature DB >> 31154498 |
Abban Edward Kofi1,2, Hashom Mohd Hakim3,4, Hussein Omar Khan3, Siti Afifah Ismail3, Anita Ghansah5, Agyemang Adjem David2, Nor Fazila Che Mat1, Geoffrey Keith Chambers6, Hisham Atan Edinur7,8,9.
Abstract
In this study, 268 samples for unrelated males belonging to the five major human subpopulation groups in Ghana (Akan, Ewe, Mole-Dagbon, Ga-Dangme and Guang) were genetically characterised for 23 Y chromosome short tandem repeat (STR) loci using the Powerplex® Y23 STR kit. A total of 263 complete haplotypes were recorded of which 258 were unique. The haplotype diversity, discriminating capacity and match probability for the pooled population data were 0.9998, 0.9627 and 0.0039, respectively. The pairwise genetic distance (RST) for the Ghanaian datasets and other reference populations deposited in the Y-STR Haplotype Reference Database (YHRD) were estimated and mapped using multidimensional scaling (MDS) plot. The Guang and Ewe were significantly different from the Akan, Mole-Dagbon and Ga-Dangme. However, the five Ghanaian datasets were all plotted close together with other African populations in the MDS data mapping.Entities:
Keywords: Forensic science; Ghana; Haplotypes; Population genetics; Y chromosome STR
Mesh:
Year: 2019 PMID: 31154498 DOI: 10.1007/s00414-019-02099-w
Source DB: PubMed Journal: Int J Legal Med ISSN: 0937-9827 Impact factor: 2.686