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Literature DB >> 31153632

CRISPR/Cas Multiplexed Biosensing: A Challenge or an Insurmountable Obstacle?

Abstract

Performing multiplex detection is still an elusive goal for molecular diagnostics. CRISPR/Cas-based biosensing has demonstrated potential for multiplex detection. Instead of being an insurmountable obstacle, CRISPR/Cas multiplexed biosensing is a realistic challenge with some recent successful applications. Strategic considerations are required to fully explore its potential in multiplex diagnostics.

Entities: Chemical

Keywords: CRISPR/Cas; biosensing; diagnostics; multiplex; nucleic acid detection

Mesh：

Year: 2019 PMID： 31153632 DOI： 10.1016/j.tibtech.2019.04.012

Source DB: PubMed Journal: Trends Biotechnol ISSN： 0167-7799 Impact factor: 19.536

Keyword Cloud
Cited

16 in total

1. Translating in vitro diagnostics from centralized laboratories to point-of-care locations using commercially-available handheld meters.

Authors: JingJing Zhang; Tian Lan; Yi Lu
Journal: Trends Analyt Chem Date: 2019-12-23 Impact factor: 12.296

2. Dynamic Aqueous Multiphase Reaction System for One-Pot CRISPR-Cas12a-Based Ultrasensitive and Quantitative Molecular Diagnosis.

Authors: Kun Yin; Xiong Ding; Ziyue Li; Hui Zhao; Kumarasen Cooper; Changchun Liu
Journal: Anal Chem Date: 2020-05-22 Impact factor: 6.986

CRISPR/Cas Multiplexed Biosensing: A Challenge or an Insurmountable Obstacle?

1. Translating in vitro diagnostics from centralized laboratories to point-of-care locations using commercially-available handheld meters.

2. Dynamic Aqueous Multiphase Reaction System for One-Pot CRISPR-Cas12a-Based Ultrasensitive and Quantitative Molecular Diagnosis.

Review 3. COVID-19 Diagnostic Strategies Part II: Protein-Based Technologies.

4. Futuristic CRISPR-based biosensing in the cloud and internet of things era: an overview.

Review 5. CRISPR-based detection of SARS-CoV-2: A review from sample to result.

Review 6. COVID-19 Diagnostic Strategies. Part I: Nucleic Acid-Based Technologies.

Review 7. Multiplexed Profiling of Extracellular Vesicles for Biomarker Development.

Review 8. Current methods for diagnosis of human coronaviruses: pros and cons.

9. Bright fluorescent nucleic acid detection with CRISPR-Cas12a and poly(thymine) templated copper nanoparticles.

Review 10. Cytokines: From Clinical Significance to Quantification.