E Yardimci1, E Aysan1, U O Idiz2, H Akbulut1, S Yigman1. 1. "Bezmialem Vakif" University, Dept. of General Surgery, Turkey. 2. Sisli Hamidiye Etfal Egitim ve Arastirma Hastanesi, Dept. of General Surgery Istanbul, Turkey.
Abstract
CONTEXT: It is unclear whether treatment is necessary for transient moderate hypocalcaemia occurring after total thyroidectomy; if it is present, it is unclear which treatment modality should be preferred. OBJECTIVE: To investigate both the necessity and effectiveness of different treatment approaches of oral and/or intravenous calcium treatment in patients with transient, postoperative, moderate hypocalcaemia. DESIGN: This is a case control study made between June 2014 and June 2015. SUBJECTS AND METHODS: Forty-five patients who had serum calcium levels 6 hours after total thyroidectomy between 7.5-8 mg/dL were divided into three equal groups: an oral calcium administration group, an intravenous calcium administration group and a no-treatment group. Serum calcium and parathyroid hormone levels were measured preoperatively and on postoperative days 1, 2, 5 and 10. RESULTS: For post-thyroidectomy patients with serum calcium 7.5-8 mg/dL in the early postoperative period, no significant difference in serum calcium or parathyroid hormone was detected between groups. CONCLUSIONS: Follow-up without treatment seems to be the most effective approach for moderate hypocalcaemia occurring in the early period following total thyroidectomy; this suggests that intravenous treatment should be avoided.
CONTEXT: It is unclear whether treatment is necessary for transient moderate hypocalcaemia occurring after total thyroidectomy; if it is present, it is unclear which treatment modality should be preferred. OBJECTIVE: To investigate both the necessity and effectiveness of different treatment approaches of oral and/or intravenous calcium treatment in patients with transient, postoperative, moderate hypocalcaemia. DESIGN: This is a case control study made between June 2014 and June 2015. SUBJECTS AND METHODS: Forty-five patients who had serum calcium levels 6 hours after total thyroidectomy between 7.5-8 mg/dL were divided into three equal groups: an oral calcium administration group, an intravenous calcium administration group and a no-treatment group. Serum calcium and parathyroid hormone levels were measured preoperatively and on postoperative days 1, 2, 5 and 10. RESULTS: For post-thyroidectomy patients with serum calcium 7.5-8 mg/dL in the early postoperative period, no significant difference in serum calcium or parathyroid hormone was detected between groups. CONCLUSIONS: Follow-up without treatment seems to be the most effective approach for moderate hypocalcaemia occurring in the early period following total thyroidectomy; this suggests that intravenous treatment should be avoided.
Authors: Celestino Pio Lombardi; Marco Raffaelli; Pietro Princi; Stefano Santini; Mauro Boscherini; Carmela De Crea; Emanuela Traini; Anna Maria D'Amore; Cinzia Carrozza; Cecilia Zuppi; Rocco Bellantone Journal: Surgery Date: 2004-12 Impact factor: 3.982
Authors: Alexandre de Andrade Sousa; José Maria Porcaro Salles; João Marcos Arantes Soares; Gustavo Meyer de Moraes; Jomar Rezende Carvalho; Paulo Roberto Savassi Rocha Journal: World J Surg Date: 2010-05 Impact factor: 3.352
Authors: Rocco Bellantone; Celestino Pio Lombardi; Marco Raffaelli; Mauro Boscherini; Pier Francesco Alesina; Carmela De Crea; Emanuela Traini; Pietro Princi Journal: Surgery Date: 2002-12 Impact factor: 3.982
Authors: James E Wiseman; Matthew Mossanen; Philip H G Ituarte; Jonathan M T Bath; Michael W Yeh Journal: World J Surg Date: 2010-03 Impact factor: 3.352