| Literature DB >> 31148109 |
Frantisek Kristek1, Marian Grman2, Karol Ondrias2.
Abstract
The chapter describes protocols and pitfalls in in vivo studies of drug effects on anesthetized rats. It focuses on the preparation of Na2S, Na2S4, and "SSNO- mix" solutions for rat intravenous administration, surgical preparation of jugular vein for drug administration, and preparation of carotid and tail arteries for recording of arterial pulse waveform (APW) at high resolution. It describes evaluation of ten hemodynamic parameters from APW and measurement of apparent pulse wave velocity.Entities:
Keywords: Arterial pulse waveform; Carotid artery; H2S; Hemodynamic parameters; Jugular vein; Na2S4; Rat blood pressure; SSNO
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Year: 2019 PMID： 31148109 DOI： 10.1007/978-1-4939-9528-8_8
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745