Literature DB >> 31147776

Does treatment-resistant hypertension exist in children? A review of the evidence.

Ian Macumber1, Joseph T Flynn2.   

Abstract

Treatment-resistant hypertension (TRH) is a well-described condition in adult patients that is associated with poor clinical outcomes. While case reports of hypertension resistant to therapy in children have been published, it is unclear if TRH truly exists in childhood. This educational review will briefly summarize recent evidence and recommendations for TRH in adults, as well as will review the literature regarding medically resistant hypertension in children and adolescents. Finally, we propose a clinical approach for evaluation hypertensive children and adolescents with apparent treatment resistance.

Entities:  

Keywords:  Apparent resistant hypertension of childhood; Children and adolescents; Pediatrics; Treatment-resistant hypertension

Mesh:

Substances:

Year:  2019        PMID: 31147776     DOI: 10.1007/s00467-019-04268-w

Source DB:  PubMed          Journal:  Pediatr Nephrol        ISSN: 0931-041X            Impact factor:   3.714


  43 in total

Review 1.  Improvement in blood pressure with inhibition of the epithelial sodium channel in blacks with hypertension.

Authors:  Chandan Saha; George J Eckert; Walter T Ambrosius; Tae-Yon Chun; Mary Anne Wagner; Qianqian Zhao; J Howard Pratt
Journal:  Hypertension       Date:  2005-08-22       Impact factor: 10.190

Review 2.  Systematic review and meta-analysis of the prevalence of resistant hypertension in treated hypertensive populations.

Authors:  Dmitrij Achelrod; Ulrich Wenzel; Simon Frey
Journal:  Am J Hypertens       Date:  2014-08-25       Impact factor: 2.689

3.  Clinical Practice Guideline for Screening and Management of High Blood Pressure in Children and Adolescents.

Authors:  Joseph T Flynn; David C Kaelber; Carissa M Baker-Smith; Douglas Blowey; Aaron E Carroll; Stephen R Daniels; Sarah D de Ferranti; Janis M Dionne; Bonita Falkner; Susan K Flinn; Samuel S Gidding; Celeste Goodwin; Michael G Leu; Makia E Powers; Corinna Rea; Joshua Samuels; Madeline Simasek; Vidhu V Thaker; Elaine M Urbina
Journal:  Pediatrics       Date:  2017-08-21       Impact factor: 7.124

4.  Renal denervation for severe hypertension in a small child with Turner syndrome: miniaturisation of the procedure and results.

Authors:  Alice Bonanni; Francesco Pasetti; Gian Marco Ghiggeri; Carlo Gandolfo
Journal:  BMJ Case Rep       Date:  2015-03-10

5.  Resistant hypertension: diagnosis, evaluation, and treatment: a scientific statement from the American Heart Association Professional Education Committee of the Council for High Blood Pressure Research.

Authors:  David A Calhoun; Daniel Jones; Stephen Textor; David C Goff; Timothy P Murphy; Robert D Toto; Anthony White; William C Cushman; William White; Domenic Sica; Keith Ferdinand; Thomas D Giles; Bonita Falkner; Robert M Carey
Journal:  Circulation       Date:  2008-06-24       Impact factor: 29.690

6.  2013 ESH/ESC Guidelines for the management of arterial hypertension: the Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC).

Authors:  Giuseppe Mancia; Robert Fagard; Krzysztof Narkiewicz; Josep Redón; Alberto Zanchetti; Michael Böhm; Thierry Christiaens; Renata Cifkova; Guy De Backer; Anna Dominiczak; Maurizio Galderisi; Diederick E Grobbee; Tiny Jaarsma; Paulus Kirchhof; Sverre E Kjeldsen; Stéphane Laurent; Athanasios J Manolis; Peter M Nilsson; Luis Miguel Ruilope; Roland E Schmieder; Per Anton Sirnes; Peter Sleight; Margus Viigimaa; Bernard Waeber; Faiez Zannad
Journal:  J Hypertens       Date:  2013-07       Impact factor: 4.844

Review 7.  Pediatric obstructive sleep apnea: complications, management, and long-term outcomes.

Authors:  Oscar Sans Capdevila; Leila Kheirandish-Gozal; Ehab Dayyat; David Gozal
Journal:  Proc Am Thorac Soc       Date:  2008-02-15

8.  Effect of renal denervation on blood pressure in the presence of antihypertensive drugs: 6-month efficacy and safety results from the SPYRAL HTN-ON MED proof-of-concept randomised trial.

Authors:  David E Kandzari; Michael Böhm; Felix Mahfoud; Raymond R Townsend; Michael A Weber; Stuart Pocock; Konstantinos Tsioufis; Dimitrios Tousoulis; James W Choi; Cara East; Sandeep Brar; Sidney A Cohen; Martin Fahy; Garrett Pilcher; Kazuomi Kario
Journal:  Lancet       Date:  2018-05-23       Impact factor: 79.321

9.  Catheter-based renal sympathetic denervation for resistant hypertension: a multicentre safety and proof-of-principle cohort study.

Authors:  Henry Krum; Markus Schlaich; Rob Whitbourn; Paul A Sobotka; Jerzy Sadowski; Krzysztof Bartus; Boguslaw Kapelak; Anthony Walton; Horst Sievert; Suku Thambar; William T Abraham; Murray Esler
Journal:  Lancet       Date:  2009-03-28       Impact factor: 79.321

10.  Catheter-based renal denervation in patients with uncontrolled hypertension in the absence of antihypertensive medications (SPYRAL HTN-OFF MED): a randomised, sham-controlled, proof-of-concept trial.

Authors:  Raymond R Townsend; Felix Mahfoud; David E Kandzari; Kazuomi Kario; Stuart Pocock; Michael A Weber; Sebastian Ewen; Konstantinos Tsioufis; Dimitrios Tousoulis; Andrew S P Sharp; Anthony F Watkinson; Roland E Schmieder; Axel Schmid; James W Choi; Cara East; Anthony Walton; Ingrid Hopper; Debbie L Cohen; Robert Wilensky; David P Lee; Adrian Ma; Chandan M Devireddy; Janice P Lea; Philipp C Lurz; Karl Fengler; Justin Davies; Neil Chapman; Sidney A Cohen; Vanessa DeBruin; Martin Fahy; Denise E Jones; Martin Rothman; Michael Böhm
Journal:  Lancet       Date:  2017-08-28       Impact factor: 79.321

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