Literature DB >> 31147407

Unusual presentation of pica in iron-deficiency anaemia associated with primary biliary cholangitis.

Nneoma Kate-Joan Onuorah1, Melinda Wayde2, Gregory Beck2.   

Abstract

A 50-year-old woman presented with worsening fatigue and shortness of breath. For 2 months, she has been having increased craving for unpeeled lemons and was seen in clinic about a month prior to presentation at the emergency room. At that time, she was asymptomatic except for endorsing craving for lemons. Physical exam findings at presentation noted obesity, sinus tachycardia, pallor, mild scleral jaundice and no other stigmata for chronic liver disease. Her labs suggested iron-deficiency anaemia (IDA), elevated liver enzymes and positive antimitochondrial antibody titre. Abdominal ultrasound and CT scan showed mild scarring. She was diagnosed with primary biliary cholangitis with portal hypertension complicated by oesophageal varices and IDA. Interventions included blood transfusion, oesophageal banding and treatment with ursodeoxycholic acid. Her craving for lemons, shortness of breath and fatigue resolved within 1 week. With ongoing outpatient follow-up and oesophageal variceal surveillance, she continues to do well. © BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  GI bleeding; liver disease; pancreas and biliary tract; varices

Mesh:

Substances:

Year:  2019        PMID: 31147407      PMCID: PMC6557326          DOI: 10.1136/bcr-2018-227316

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  18 in total

1.  Craving lemons: another form of pica in iron deficiency.

Authors:  Satheesh K Kathula
Journal:  Am J Med       Date:  2008-07       Impact factor: 4.965

2.  Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 37-1998. A 41-year-old woman with anemia and severe thrombocytopenia.

Authors: 
Journal:  N Engl J Med       Date:  1998-12-10       Impact factor: 91.245

3.  Pica: a compulsion caused by iron deficiency.

Authors:  W H Crosby
Journal:  Br J Haematol       Date:  1976-10       Impact factor: 6.998

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Authors:  C A Coltman
Journal:  Arch Intern Med       Date:  1971-09

5.  Prevalence and associated factors with esophageal varices in early primary biliary cirrhosis.

Authors:  Fusao Ikeda; Ryoichi Okamoto; Nobuyuki Baba; Shin-ichi Fujioka; Bon Shoji; Kazuhisa Yabushita; Masaharu Ando; Shuji Matsumura; Junichi Kubota; Tetsuya Yasunaka; Yasuhiro Miyake; Yoshiaki Iwasaki; Haruhiko Kobashi; Hiroyuki Okada; Kazuhide Yamamoto
Journal:  J Gastroenterol Hepatol       Date:  2012-08       Impact factor: 4.029

Review 6.  Pica: common but commonly missed.

Authors:  E A Rose; J H Porcerelli; A V Neale
Journal:  J Am Board Fam Pract       Date:  2000 Sep-Oct

7.  Geophagia in rural Mississippi: environmental and cultural contexts and nutritional implications.

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Journal:  Am J Clin Nutr       Date:  1979-10       Impact factor: 7.045

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Authors:  Robert F Kushner; Briana Gleason; Victoria Shanta-Retelny
Journal:  J Am Diet Assoc       Date:  2004-09

9.  Pica associated with iron deficiency or depletion: clinical and laboratory correlates in 262 non-pregnant adult outpatients.

Authors:  James C Barton; J Clayborn Barton; Luigi F Bertoli
Journal:  BMC Blood Disord       Date:  2010-12-22

Review 10.  Micronutrient deficiencies in patients with chronic atrophic autoimmune gastritis: A review.

Authors:  Federica Cavalcoli; Alessandra Zilli; Dario Conte; Sara Massironi
Journal:  World J Gastroenterol       Date:  2017-01-28       Impact factor: 5.742

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  1 in total

Review 1.  Iron deficiency and soil-transmitted helminth infection: classic and neglected connections.

Authors:  Joel Henrique Ellwanger; Marina Ziliotto; Bruna Kulmann-Leal; José Artur Bogo Chies
Journal:  Parasitol Res       Date:  2022-10-19       Impact factor: 2.383

  1 in total

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