Suchandra Mukherjee1, Jignesh S Bulsara2, Manoja Kumar Das3, Yogendra Waratakar4, Anindya Kumar Saha1, Sunil Dubey5, Pratima Mehta5, Bini Gupta3, Arun K Singh6. 1. Department of Neonatology, Institute of Post Graduate Medical Education & Research, Kolkata, West Bengal, India. 2. Department of Obstetrics and Gynaecology, Shreemad Rajchandra Hospital, Dharampur, Valsad, Gujarat, India. 3. The INCLEN Trust International, New Delhi, India. 4. Department of Pediatrics, Shreemad Rajchandra Hospital, Dharampur, Valsad, Gujarat, India. 5. Medical Administration, Shreemad Rajchandra Hospital, Dharampur, Valsad, Gujarat, India. 6. Rashtriya Bal Swasthya Karyakram, Ministry of Health & Family Welfare, Government of India, New Delhi, India.
Abstract
OBJECTIVE: This study aimed to compare the preductal oxygen saturation (SpO2) and heart rate (HR) in newborns during the initial 5 minutes after birth with delayed cord clamping (DCC) and early cord clamping (ECC) practices at sea level. STUDY DESIGN: This prospective observational study included newborns born at >34 weeks vaginally (Dharampur, Gujarat) or through caesarean section (CS) (Kolkata, West Bengal). In Dharampur, the newborns received ECC practice (8 weeks) followed by DCC practice (10 weeks). In Kolkata, the newborns received ECC practice only (8 weeks). RESULTS: The newborns with DCC (n = 170) had significantly higher SpO2 (3-8%) throughout than those with ECC born either vaginally (n = 178) or through CS (n = 101). The newborns with DCC had slower rise in HR during the first 2 minutes than those with ECC. The 5th and 10th percentile values of SpO2 for newborns with DCC practice were higher than those with ECC practice. CONCLUSION: The trends of SpO2 and HR during the first 5 minutes after birth indicate a relatively smoother cardiopulmonary transition by delaying cord clamping till placental delivery compared with early clamping. The reference ranges can be used for Indian newborns born by uncomplicated vaginal delivery with DCC during the first 5 minutes. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.
OBJECTIVE: This study aimed to compare the preductal oxygen saturation (SpO2) and heart rate (HR) in newborns during the initial 5 minutes after birth with delayed cord clamping (DCC) and early cord clamping (ECC) practices at sea level. STUDY DESIGN: This prospective observational study included newborns born at >34 weeks vaginally (Dharampur, Gujarat) or through caesarean section (CS) (Kolkata, West Bengal). In Dharampur, the newborns received ECC practice (8 weeks) followed by DCC practice (10 weeks). In Kolkata, the newborns received ECC practice only (8 weeks). RESULTS: The newborns with DCC (n = 170) had significantly higher SpO2 (3-8%) throughout than those with ECC born either vaginally (n = 178) or through CS (n = 101). The newborns with DCC had slower rise in HR during the first 2 minutes than those with ECC. The 5th and 10th percentile values of SpO2 for newborns with DCC practice were higher than those with ECC practice. CONCLUSION: The trends of SpO2 and HR during the first 5 minutes after birth indicate a relatively smoother cardiopulmonary transition by delaying cord clamping till placental delivery compared with early clamping. The reference ranges can be used for Indian newborns born by uncomplicated vaginal delivery with DCC during the first 5 minutes. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.
Authors: Vishal Kapadia; Ju Lee Oei; Neil Finer; Wade Rich; Yacov Rabi; Ian M Wright; Denise Rook; Marijn J Vermeulen; William O Tarnow-Mordi; John P Smyth; Kei Lui; Steven Brown; Ola D Saugstad; Maximo Vento Journal: Resuscitation Date: 2021-08-20 Impact factor: 6.251