Literature DB >> 31142143

Ligand-independent activation of the P2X7 receptor by Hsp90 inhibition stimulates motor neuron apoptosis.

Amy L Strayer1, Cassandra N Dennys-Rivers2, Karina C Ricart3, Narae Bae4, Joseph S Beckman5, Maria Clara Franco5, Alvaro G Estevez5.   

Abstract

Entities:  

Keywords:  Fas; Heat shock protein 90; P2X7; apoptosis; motor neuron; phosphatase and tensin homolog

Mesh：

Substances：

Year:  2019        PMID： 31142143      PMCID： PMC6690143          DOI： 10.1177/1535370219853798

Source DB:  PubMed          Journal:  Exp Biol Med (Maywood)        ISSN： 1535-3699


× No keyword cloud information.
  91 in total

1.  Liposome-delivered superoxide dismutase prevents nitric oxide-dependent motor neuron death induced by trophic factor withdrawal.

Authors:  A G Estévez; J B Sampson; Y X Zhuang; N Spear; G J Richardson; J P Crow; M M Tarpey; L Barbeito; J S Beckman
Journal:  Free Radic Biol Med       Date:  2000-02-01       Impact factor: 7.376

Review 2.  Structure and in vivo function of Hsp90.

Authors:  L H Pearl; C Prodromou
Journal:  Curr Opin Struct Biol       Date:  2000-02       Impact factor: 6.809

3.  Negative regulation of the forkhead transcription factor FKHR by Akt.

Authors:  E D Tang; G Nuñez; F G Barr; K L Guan
Journal:  J Biol Chem       Date:  1999-06-11       Impact factor: 5.157

4.  Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor.

Authors:  A Brunet; A Bonni; M J Zigmond; M Z Lin; P Juo; L S Hu; M J Anderson; K C Arden; J Blenis; M E Greenberg
Journal:  Cell       Date:  1999-03-19       Impact factor: 41.582

5.  Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase.

Authors:  A G Estévez; J P Crow; J B Sampson; C Reiter; Y Zhuang; G J Richardson; M M Tarpey; L Barbeito; J S Beckman
Journal:  Science       Date:  1999-12-24       Impact factor: 47.728

6.  Receptors of the glial cell line-derived neurotrophic factor family of neurotrophic factors signal cell survival through the phosphatidylinositol 3-kinase pathway in spinal cord motoneurons.

Authors:  R M Soler; X Dolcet; M Encinas; J Egea; J R Bayascas; J X Comella
Journal:  J Neurosci       Date:  1999-11-01       Impact factor: 6.167

7.  Activation of phosphatidylinositol 3-kinase, but not extracellular-regulated kinases, is necessary to mediate brain-derived neurotrophic factor-induced motoneuron survival.

Authors:  X Dolcet; J Egea; R M Soler; D Martin-Zanca; J X Comella
Journal:  J Neurochem       Date:  1999-08       Impact factor: 5.372

8.  Mechanism of phosphorylation of protein kinase B/Akt by a constitutively active 3-phosphoinositide-dependent protein kinase-1.

Authors:  M J Wick; L Q Dong; R A Riojas; F J Ramos; F Liu
Journal:  J Biol Chem       Date:  2000-12-22       Impact factor: 5.157

9.  GFRalpha 1 is required for development of distinct subpopulations of motoneuron.

Authors:  A Garcès; G Haase; M S Airaksinen; J Livet; P Filippi; O deLapeyrière
Journal:  J Neurosci       Date:  2000-07-01       Impact factor: 6.167

10.  Programmed cell death of embryonic motoneurons triggered through the Fas death receptor.

Authors:  C Raoul; C E Henderson; B Pettmann
Journal:  J Cell Biol       Date:  1999-11-29       Impact factor: 10.539
View more
  2 in total

1.  Hsp90-mediated regulation of DYRK3 couples stress granule disassembly and growth via mTORC1 signaling.

Authors:  Laura Mediani; Francesco Antoniani; Veronica Galli; Jonathan Vinet; Arianna Dorotea Carrà; Ilaria Bigi; Vadreenath Tripathy; Tatiana Tiago; Marco Cimino; Giuseppina Leo; Triana Amen; Daniel Kaganovich; Cristina Cereda; Orietta Pansarasa; Jessica Mandrioli; Priyanka Tripathi; Dirk Troost; Eleonora Aronica; Johannes Buchner; Anand Goswami; Jared Sterneckert; Simon Alberti; Serena Carra
Journal:  EMBO Rep       Date:  2021-03-19       Impact factor: 8.807

2.  Peroxynitrite nitration of Tyr 56 in Hsp90 induces PC12 cell death through P2X7R-dependent PTEN activation.

Authors:  Megan Jandy; Asra Noor; Pascal Nelson; Cassandra N Dennys; Isabella M Karabinas; Jeanine C Pestoni; Gautam D Singh; Lam Luc; Rachel Devyldere; Nathalie Perdomo; Catherine E Mitchell; Levi Adams; Marisa A Fuse; Francine A Mendoza; Carrie L Marean-Reardon; Ryan A Mehl; Alvaro G Estevez; Maria Clara Franco
Journal:  Redox Biol       Date:  2022-01-26       Impact factor: 11.799
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.