Paula Tegelberg1, Tellervo Tervonen1, Matti Knuuttila2, Jari Jokelainen3,4, Sirkka Keinänen-Kiukaanniemi4,5,6, Juha Auvinen4,6,7, Pekka Ylöstalo1,2. 1. Research Unit of Oral Health Sciences, Faculty of Medicine, University of Oulu, Oulu, Finland. 2. Department of Oral and Maxillofacial Surgery, Oulu University Hospital, Oulu, Finland. 3. Center for Life Course Epidemiology and Systems Medicine, University of Oulu and Unit of Primary Care, Oulu, Finland. 4. Medical Research Center, Oulu University Hospital and University of Oulu, Oulu, Finland. 5. Healthcare and Social Services of Selänne, Pyhäjärvi, Finland. 6. Faculty of Medicine, Center for Life Course Health Research, Health Center of Oulu, University of Oulu, Oulu, Finland. 7. Oulunkaari Health Center, Ii, Finland.
Abstract
AIM: To investigate whether the metabolic syndrome (MetS) is associated with deepened periodontal pockets and alveolar bone loss. MATERIALS AND METHODS: This study was based on a subpopulation of the Northern Finland Birth Cohort 1966 survey (n = 1964). The criteria of the AHA/NHLBI were used to determine MetS. The analyses were based on the metabolic data at ages 31 and 46, and probing pocket depth and alveolar bone level data at age 46. Relative risks (RR, 95% CI) were estimated using Poisson regression models. RESULTS: Relative risks for PD ≥ 4 mm and BL ≥ 5 mm were higher in individuals with an exposure to MetS ≥ 15 years (RR 1.8, 95% CI 1.6-2.1 and RR 1.5, 95% CI 1.3-1.9, respectively) than in those whose exposure was <15 years (RR 1.2, 95% CI 1.1-1.3 and RR 1.1, 95% CI 1.0-1.3, respectively). Consistently stronger associations were found in never smokers. Women showed stronger associations of MetS with PD ≥ 4 mm than men. The association with BL ≥ 5 mm was observed only in men. CONCLUSION: A long-term exposure by MetS was associated independently and in an exposure-dependent manner with periodontal pockets and alveolar bone level.
AIM: To investigate whether the metabolic syndrome (MetS) is associated with deepened periodontal pockets and alveolar bone loss. MATERIALS AND METHODS: This study was based on a subpopulation of the Northern Finland Birth Cohort 1966 survey (n = 1964). The criteria of the AHA/NHLBI were used to determine MetS. The analyses were based on the metabolic data at ages 31 and 46, and probing pocket depth and alveolar bone level data at age 46. Relative risks (RR, 95% CI) were estimated using Poisson regression models. RESULTS: Relative risks for PD ≥ 4 mm and BL ≥ 5 mm were higher in individuals with an exposure to MetS ≥ 15 years (RR 1.8, 95% CI 1.6-2.1 and RR 1.5, 95% CI 1.3-1.9, respectively) than in those whose exposure was <15 years (RR 1.2, 95% CI 1.1-1.3 and RR 1.1, 95% CI 1.0-1.3, respectively). Consistently stronger associations were found in never smokers. Women showed stronger associations of MetS with PD ≥ 4 mm than men. The association with BL ≥ 5 mm was observed only in men. CONCLUSION: A long-term exposure by MetS was associated independently and in an exposure-dependent manner with periodontal pockets and alveolar bone level.
Authors: Tanja Nordström; Jouko Miettunen; Juha Auvinen; Leena Ala-Mursula; Sirkka Keinänen-Kiukaanniemi; Juha Veijola; Marjo-Riitta Järvelin; Sylvain Sebert; Minna Männikkö Journal: Int J Epidemiol Date: 2021-08-29 Impact factor: 7.196