Literature DB >> 31140067

Biologic Treatment for Hidradenitis Suppurativa.

Kelsey S Flood1, Martina L Porter1, Alexa B Kimball2.   

Abstract

Patients with hidradenitis suppurativa (HS) are often undertreated and there are limited efficacious therapies available for treating this population. Biologics are an emerging therapeutic modality used in the management of many inflammatory conditions including HS. Implementation of biologics is typically reserved for moderate-to-severe cases or in those cases that are refractory to treatment. Though many biologics have been trialed for use in HS, only one biologic, adalimumab, is currently US FDA (Food and Drug Administration) approved for the treatment of moderate-to-severe HS. Limitations in the use of biologics for HS include the many scoring systems utilized in research studies and the relatively few well-designed, adequately powered clinical trials.

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Year:  2019        PMID: 31140067     DOI: 10.1007/s40257-019-00439-5

Source DB:  PubMed          Journal:  Am J Clin Dermatol        ISSN: 1175-0561            Impact factor:   7.403


  3 in total

Review 1.  Medical Management of Hidradenitis Suppurativa with Non-Biologic Therapy: What's New?

Authors:  Soha Ghanian; Mika Yamanaka-Takaichi; Haley B Naik; Afsaneh Alavi
Journal:  Am J Clin Dermatol       Date:  2022-01-06       Impact factor: 6.233

2.  Incidence of Skin Cancer in Patients With Chronic Inflammatory Cutaneous Diseases on Targeted Therapies: A Systematic Review and Meta-Analysis of Observational Studies.

Authors:  Salvatore Crisafulli; Lucrezia Bertino; Andrea Fontana; Fabrizio Calapai; Ylenia Ingrasciotta; Massimiliano Berretta; Gianluca Trifirò; Claudio Guarneri
Journal:  Front Oncol       Date:  2021-06-03       Impact factor: 6.244

Review 3.  Hidradenitis Suppurativa and 1-Carbon Metabolism: Role of Gut Microbiome, Matrix Metalloproteinases, and Hyperhomocysteinemia.

Authors:  Jack Molnar; Carissa Jo Mallonee; Dragana Stanisic; Rubens P Homme; Akash K George; Mahavir Singh; Suresh C Tyagi
Journal:  Front Immunol       Date:  2020-08-19       Impact factor: 7.561

  3 in total

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