Literature DB >> 31139854

[Drug treatment of Alzheimer's dementia : Status quo and perspectives].

P Müller1, M Fendt2,3, N G Müller4,3,5.   

Abstract

Alzheimer's disease (AD) is a neurodegenerative disease of the central nervous system. AD is characterized by progressive impairments of memory as well as other cognitive functions and an increasing loss of autonomy in everyday life. This review article provides an overview of the current state-of-the-art (symptomatic) pharmacological treatment of Alzheimer's disease, specifics in the context of concomitant neuropsychiatric symptoms in multimorbid patients, and drugs currently under development that have a potentially causal (disease modifying) effect are also mentioned.

Entities:  

Keywords:  Aging; Alzheimer disease, prevention; Cholinesterase inhibitors; Memantine; Multimorbidity

Mesh:

Substances:

Year:  2019        PMID: 31139854     DOI: 10.1007/s00108-019-0625-4

Source DB:  PubMed          Journal:  Internist (Berl)        ISSN: 0020-9554            Impact factor:   0.743


  2 in total

Review 1.  Lactate and BDNF: Key Mediators of Exercise Induced Neuroplasticity?

Authors:  Patrick Müller; Yves Duderstadt; Volkmar Lessmann; Notger G Müller
Journal:  J Clin Med       Date:  2020-04-15       Impact factor: 4.241

2.  Structural MRI of the basal forebrain as predictor of cognitive response to galantamine in healthy older adults-A randomized controlled double-blinded crossover study.

Authors:  Patrick Müller; Anne-Katrin Vellage; Marlen Schmicker; Inga Menze; Michel J Grothe; Stefan J Teipel; Notger G Müller
Journal:  Alzheimers Dement (N Y)       Date:  2021-04-05
  2 in total

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