Lucas Villalta Santos1, Jamile Benite Palma Lopes, Natália Almeida Carvalho Duarte, Manuela Galli, Luanda André Collange Grecco, Claudia Santos Oliveira. 1. Health Sciences (Mr Santos, Ms Lopes, and Drs Duarte and Oliveira), Santa Casa de São Paulo School of Medical Sciences, São Paulo, SP, Brazil; Vento Leste-Specialized Childcare Habilitation (Mr Santos and Dr Grecco), Sorocaba, SP, Brazil; Department of Electronic Information and Bioengineering (Dr Galli), Politecnico di Milano, Milan, Italy; Laboratory of Integrated Human Movements (Dr Grecco), Universidade de Sorocaba, Sorocaba, SP, Brazil; Center of Pediatric Neurostimulation (Dr Grecco), São Paulo, SP, Brazil; University Center of Anápolis (Dr Oliveira), Anápolis, GO, Brazil.
Abstract
PURPOSE: To compare the clinical and functional effects of treadmill training combined with anodic transcranial direct current stimulation (atDCS) on the primary motor cortex (Cz), specifically on the area of motor cortex representation of the lower limbs, and on the cerebellum (Cb) in children with spastic cerebral palsy (CP). METHODS:Thirty children and adolescents with spastic CP will be randomly allocated in 3 groups: (1) treadmill training and atDCS on Cz; (2) treadmill training and atDCS on Cb; (3) treadmill training and shamtDCS on Cz. Evaluations of gait spatial-temporal parameters, functional mobility, functional balance, gross motor function, and functional performance will be performed 1 week before intervention and 1 week, 1 month, and 3 months after intervention. Every 3 months the participants will cross over groups. DISCUSSION: This is a protocol for an intervention study comparing the clinical and functional effects of atDCS over Cz and Cb.
RCT Entities:
PURPOSE: To compare the clinical and functional effects of treadmill training combined with anodic transcranial direct current stimulation (atDCS) on the primary motor cortex (Cz), specifically on the area of motor cortex representation of the lower limbs, and on the cerebellum (Cb) in children with spastic cerebral palsy (CP). METHODS: Thirty children and adolescents with spastic CP will be randomly allocated in 3 groups: (1) treadmill training and atDCS on Cz; (2) treadmill training and atDCS on Cb; (3) treadmill training and sham tDCS on Cz. Evaluations of gait spatial-temporal parameters, functional mobility, functional balance, gross motor function, and functional performance will be performed 1 week before intervention and 1 week, 1 month, and 3 months after intervention. Every 3 months the participants will cross over groups. DISCUSSION: This is a protocol for an intervention study comparing the clinical and functional effects of atDCS over Cz and Cb.
Authors: Maria Dolores Apolo-Arenas; Aline Ferreira de Araújo Jerônimo; Alejandro Caña-Pino; Orlando Fernandes; Joana Alegrete; Jose Alberto Parraca Journal: J Pers Med Date: 2021-06-26