Literature DB >> 31135499

A 360° Rotational Positioning Protocol of Organ Donors May Increase Lungs Available for Transplantation.

Marissa A Mendez1, Alyssa J Fesmire1, Scott S Johnson2, Dustin R Neel1, Lori E Markham3, Jody C Olson4, Melissa Ott3, Harbaksh Sangha5, Donald G Vasquez6, Stevan P Whitt7, Harry E Wilkins3, Michael Moncure1.   

Abstract

OBJECTIVES: To evaluate the improvement in lung donation and immediate lung function after the implementation of a 360° rotational positioning protocol within an organ procurement organization in the Midwest.
DESIGN: Retrospective observational study.
SETTING: The Midwest Transplant Network from 2005 to 2017. Rotational positioning of donors began in 2008.
SUBJECTS: Potential deceased lung donors.
INTERVENTIONS: A 360° rotational protocol. Presence of immediate lung function in recipients, change in PaO2:FIO2 ratio during donor management, initial and final PaO2:FIO2 ratio, and proportion of lungs donated were measured. Outcomes were compared between rotated and nonrotated donors.
MEASUREMENTS AND MAIN RESULTS: A total of 693 donors were analyzed. The proportion of lung donations increased by 10%. The difference between initial PaO2:FIO2 ratio and final PaO2:FIO2 ratio was significantly different between rotated and nonrotated donors (36 ± 116 vs 104 ± 148; p < 0.001). Lungs transplanted from rotated donors had better immediate function than those from nonrotated donors (99.5% vs 68%; p < 0.001).
CONCLUSIONS: There was a statistically significant increase in lung donations after implementing rotational positioning of deceased donors. Rotational positioning significantly increased the average difference in PaO2:FIO2 ratios. There was also superior lung function in the rotated group. The authors recommend that organ procurement organizations consider adopting a rotational positioning protocol for donors to increase the lungs available for transplantation.

Entities:  

Year:  2019        PMID: 31135499     DOI: 10.1097/CCM.0000000000003805

Source DB:  PubMed          Journal:  Crit Care Med        ISSN: 0090-3493            Impact factor:   7.598


  1 in total

1.  Successful lung transplantation after prone positioning in an ineligible donor: a case report.

Authors:  Eunjeong Son; Jinook Jang; Woo Hyun Cho; Dohyung Kim; Hye Ju Yeo
Journal:  Gen Thorac Cardiovasc Surg       Date:  2021-06-22
  1 in total

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