Benedikt Schrage1,2, Dirk Westermann1,2. 1. Department of General and Interventional Cardiology, University Heart Center Hamburg. 2. German Center of Cardiovascular Research, Partner Side Hamburg/Kiel/Luebeck, Germany.
Abstract
PURPOSE OF REVIEW: The main purpose of this review is to highlight and summarize recently published studies on the usage of short-term mechanical circulatory support devices for treatment of cardiogenic shock. Importantly, this review will focus on percutaneously implanted devices. RECENT FINDINGS: In recent years, usage of active mechanical circulatory support devices, such as catheter-based left ventricular-assist devices and veno-arterial extracorporeal membrane oxygenation devices, has been widely adopted. Several device-specific strategies have been proposed to improve outcome of treated patients with cardiogenic shock, ranging from early identification and treatment of patients via dedicated shock protocols to combinatory usage of these devices. However, this is not supported by prospective, randomized trials but by retrospective analysis, which are significantly impacted by bias. SUMMARY: Randomized, controlled trials are utterly needed to guide treatment with mechanical circulatory support for patients with cardiogenic shock. Importantly, such trials should focus patient selection criteria.
PURPOSE OF REVIEW: The main purpose of this review is to highlight and summarize recently published studies on the usage of short-term mechanical circulatory support devices for treatment of cardiogenic shock. Importantly, this review will focus on percutaneously implanted devices. RECENT FINDINGS: In recent years, usage of active mechanical circulatory support devices, such as catheter-based left ventricular-assist devices and veno-arterial extracorporeal membrane oxygenation devices, has been widely adopted. Several device-specific strategies have been proposed to improve outcome of treated patients with cardiogenic shock, ranging from early identification and treatment of patients via dedicated shock protocols to combinatory usage of these devices. However, this is not supported by prospective, randomized trials but by retrospective analysis, which are significantly impacted by bias. SUMMARY: Randomized, controlled trials are utterly needed to guide treatment with mechanical circulatory support for patients with cardiogenic shock. Importantly, such trials should focus patient selection criteria.
Authors: Alexander M Bernhardt; Benedikt Schrage; Ines Schroeder; Georg Trummer; Dirk Westermann; Hermann Reichenspurner Journal: Dtsch Arztebl Int Date: 2022-04-01 Impact factor: 8.251
Authors: Benedikt Schrage; Peter Moritz Becher; Alexander Bernhardt; Hiram Bezerra; Stefan Blankenberg; Stefan Brunner; Pascal Colson; Gaston Cudemus Deseda; Salim Dabboura; Dennis Eckner; Matthias Eden; Ingo Eitel; Derk Frank; Norbert Frey; Masaki Funamoto; Alina Goßling; Tobias Graf; Christian Hagl; Paulus Kirchhof; Danny Kupka; Ulf Landmesser; Jerry Lipinski; Mathew Lopes; Nicolas Majunke; Octavian Maniuc; Daniel McGrath; Sven Möbius-Winkler; David A Morrow; Marc Mourad; Curt Noel; Peter Nordbeck; Martin Orban; Federico Pappalardo; Sandeep M Patel; Matthias Pauschinger; Vittorio Pazzanese; Hermann Reichenspurner; Marcus Sandri; P Christian Schulze; Robert H G Schwinger; Jan-Malte Sinning; Adem Aksoy; Carsten Skurk; Lukasz Szczanowicz; Holger Thiele; Franziska Tietz; Anubodh Varshney; Lukas Wechsler; Dirk Westermann Journal: Circulation Date: 2020-10-09 Impact factor: 29.690
Authors: Isabell Yan; Benedikt Schrage; Jessica Weimann; Salim Dabboura; Rafel Hilal; Benedikt N Beer; Peter Moritz Becher; Moritz Seiffert; Christina Magnussen; Renate B Schnabel; Paulus Kirchhof; Stefan Blankenberg; Dirk Westermann Journal: ESC Heart Fail Date: 2021-03-24
Authors: Benedikt Schrage; Jessica Weimann; Salim Dabboura; Isabell Yan; Rafel Hilal; Peter Moritz Becher; Moritz Seiffert; Alexander M Bernhardt; Stefan Kluge; Hermann Reichenspurner; Stefan Blankenberg; Dirk Westermann Journal: J Clin Med Date: 2020-03-28 Impact factor: 4.241
Authors: Corinna N Lang; Klaus Kaier; Viviane Zotzmann; Peter Stachon; Torben Pottgiesser; Constantin von Zur Muehlen; Manfred Zehender; Daniel Duerschmied; Bonaventura Schmid; Christoph Bode; Tobias Wengenmayer; Dawid L Staudacher Journal: Clin Res Cardiol Date: 2020-11-30 Impact factor: 5.460