Literature DB >> 31135336

Getting to the heart of cardiovascular evolution in humans.

Alex Pollen1,2, Bryan J Pavlovic1,2.   

Abstract

Differences in the response of cardiomyocytes to oxygen deprivation in humans and chimpanzees may explain why humans are more prone to certain heart diseases.
© 2019, Pollen and Pavlovic.

Entities:  

Keywords:  cardiomyocytes; chimpanzee; evolutionary biology; human; hypoxia; iPSCs

Mesh:

Year:  2019        PMID: 31135336      PMCID: PMC6538371          DOI: 10.7554/eLife.47807

Source DB:  PubMed          Journal:  Elife        ISSN: 2050-084X            Impact factor:   8.140


  10 in total

Review 1.  The role of regulatory variation in complex traits and disease.

Authors:  Frank W Albert; Leonid Kruglyak
Journal:  Nat Rev Genet       Date:  2015-02-24       Impact factor: 53.242

Review 2.  Comparative Pathology of Aging Great Apes: Bonobos, Chimpanzees, Gorillas, and Orangutans.

Authors:  L J Lowenstine; R McManamon; K A Terio
Journal:  Vet Pathol       Date:  2015-12-31       Impact factor: 2.221

3.  Interstitial myocardial fibrosis in a captive chimpanzee (Pan troglodytes) population.

Authors:  Michael L Lammey; Gary B Baskin; Andrew P Gigliotti; D Rick Lee; John J Ely; Meg M Sleeper
Journal:  Comp Med       Date:  2008-08       Impact factor: 0.982

4.  Functional comparison of innate immune signaling pathways in primates.

Authors:  Luis B Barreiro; John C Marioni; Ran Blekhman; Matthew Stephens; Yoav Gilad
Journal:  PLoS Genet       Date:  2010-12-16       Impact factor: 5.917

5.  Heart disease is common in humans and chimpanzees, but is caused by different pathological processes.

Authors:  Nissi Varki; Dan Anderson; James G Herndon; Tho Pham; Christopher J Gregg; Monica Cheriyan; James Murphy; Elizabeth Strobert; Jo Fritz; James G Else; Ajit Varki
Journal:  Evol Appl       Date:  2009-02       Impact factor: 5.183

6.  The genetic architecture of gene expression levels in wild baboons.

Authors:  Jenny Tung; Xiang Zhou; Susan C Alberts; Matthew Stephens; Yoav Gilad
Journal:  Elife       Date:  2015-02-25       Impact factor: 8.140

7.  A panel of induced pluripotent stem cells from chimpanzees: a resource for comparative functional genomics.

Authors:  Irene Gallego Romero; Bryan J Pavlovic; Irene Hernando-Herraez; Xiang Zhou; Michelle C Ward; Nicholas E Banovich; Courtney L Kagan; Jonathan E Burnett; Constance H Huang; Amy Mitrano; Claudia I Chavarria; Inbar Friedrich Ben-Nun; Yingchun Li; Karen Sabatini; Trevor R Leonardo; Mana Parast; Tomas Marques-Bonet; Louise C Laurent; Jeanne F Loring; Yoav Gilad
Journal:  Elife       Date:  2015-06-23       Impact factor: 8.140

8.  Genetic variation and gene expression across multiple tissues and developmental stages in a nonhuman primate.

Authors:  Anna J Jasinska; Ivette Zelaya; Susan K Service; Christine B Peterson; Rita M Cantor; Oi-Wa Choi; Joseph DeYoung; Eleazar Eskin; Lynn A Fairbanks; Scott Fears; Allison E Furterer; Yu S Huang; Vasily Ramensky; Christopher A Schmitt; Hannes Svardal; Matthew J Jorgensen; Jay R Kaplan; Diego Villar; Bronwen L Aken; Paul Flicek; Rishi Nag; Emily S Wong; John Blangero; Thomas D Dyer; Marina Bogomolov; Yoav Benjamini; George M Weinstock; Ken Dewar; Chiara Sabatti; Richard K Wilson; J David Jentsch; Wesley Warren; Giovanni Coppola; Roger P Woods; Nelson B Freimer
Journal:  Nat Genet       Date:  2017-10-30       Impact factor: 38.330

9.  A generally conserved response to hypoxia in iPSC-derived cardiomyocytes from humans and chimpanzees.

Authors:  Michelle C Ward; Yoav Gilad
Journal:  Elife       Date:  2019-04-08       Impact factor: 8.140

10.  A Comparative Assessment of Human and Chimpanzee iPSC-derived Cardiomyocytes with Primary Heart Tissues.

Authors:  Bryan J Pavlovic; Lauren E Blake; Julien Roux; Claudia Chavarria; Yoav Gilad
Journal:  Sci Rep       Date:  2018-10-17       Impact factor: 4.379

  10 in total
  1 in total

Review 1.  Human Brain Organoid: A Versatile Tool for Modeling Neurodegeneration Diseases and for Drug Screening.

Authors:  Cuili Ma; Hwanwook Seong; Xiaowei Li; Xiao Yu; Shunliang Xu; Yujing Li
Journal:  Stem Cells Int       Date:  2022-08-25       Impact factor: 5.131

  1 in total

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