Javiera Leniz1, Irene J Higginson1, Robert Stewart2, Katherine E Sleeman1. 1. King's College London, Cicely Saunders Institute of Palliative Care, Policy & Rehabilitation, UK. 2. King's College London, Institute of Psychiatry, Psychology and Neuroscience; South London and Maudsley NHS Foundation Trust, Biomedical Research Centre, UK.
Abstract
BACKGROUND: transitions between care settings near the end-of-life for people with dementia can be distressing, lead to physical and cognitive deterioration, and may be avoidable. OBJECTIVE: to investigate determinants of end-of-life hospital transitions, and association with healthcare use, among people with dementia. DESIGN: retrospective cohort study. SETTING: electronic records from a mental health provider in London, linked to national mortality and hospital data. SUBJECTS: people with dementia who died in 2007-2016. METHODS: end-of-life hospital transitions were defined as: multiple admissions in the last 90 days (early), or any admission in the last three days of life (late). Determinants were assessed using logistic regression. RESULTS: of 8,880 people, 1,421 (16.0%) had at least one end-of-life transition: 505 (5.7%) had early, 788 (8.9%) late, and 128 (1.5%) both types. Early transitions were associated with male gender (OR 1.33, 95% CI 1.11-1.59), age (>90 vs <75 years OR 0.69, 95% CI 0.49-0.97), physical illness (OR 1.52, 95% CI 1.20-1.94), depressed mood (OR 1.49, 95% CI 1.17-1.90), and deprivation (most vs least affluent quintile OR 0.58, 95% CI 0.37-0.90). Care home residence was associated with fewer early (OR 0.63, 95% CI 0.53 to 0.76) and late (OR 0.80, 95% CI 0.65 to 0.97) transitions. Early transitions were associated with more hospital admissions throughout the last year of life compared to those with late and no transitions (mean 4.56, 1.89, 1.60; P < 0.001). CONCLUSIONS: in contrast to late transitions, early transitions are associated with higher healthcare use and characteristics that are predictable, indicating potential for prevention.
BACKGROUND: transitions between care settings near the end-of-life for people with dementia can be distressing, lead to physical and cognitive deterioration, and may be avoidable. OBJECTIVE: to investigate determinants of end-of-life hospital transitions, and association with healthcare use, among people with dementia. DESIGN: retrospective cohort study. SETTING: electronic records from a mental health provider in London, linked to national mortality and hospital data. SUBJECTS:people with dementia who died in 2007-2016. METHODS: end-of-life hospital transitions were defined as: multiple admissions in the last 90 days (early), or any admission in the last three days of life (late). Determinants were assessed using logistic regression. RESULTS: of 8,880 people, 1,421 (16.0%) had at least one end-of-life transition: 505 (5.7%) had early, 788 (8.9%) late, and 128 (1.5%) both types. Early transitions were associated with male gender (OR 1.33, 95% CI 1.11-1.59), age (>90 vs <75 years OR 0.69, 95% CI 0.49-0.97), physical illness (OR 1.52, 95% CI 1.20-1.94), depressed mood (OR 1.49, 95% CI 1.17-1.90), and deprivation (most vs least affluent quintile OR 0.58, 95% CI 0.37-0.90). Care home residence was associated with fewer early (OR 0.63, 95% CI 0.53 to 0.76) and late (OR 0.80, 95% CI 0.65 to 0.97) transitions. Early transitions were associated with more hospital admissions throughout the last year of life compared to those with late and no transitions (mean 4.56, 1.89, 1.60; P < 0.001). CONCLUSIONS: in contrast to late transitions, early transitions are associated with higher healthcare use and characteristics that are predictable, indicating potential for prevention.
Authors: Ping-Jen Chen; Chung-Han Ho; Jung-Yu Liao; Lisanne Smits; Chao A Hsiung; Sang-Ju Yu; Kai-Ping Zhang; Irene Petersen; Elizabeth L Sampson Journal: Int J Environ Res Public Health Date: 2020-12-10 Impact factor: 3.390
Authors: Nuriye Kupeli; Elizabeth L Sampson; Gerard Leavey; Jane Harrington; Sarah Davis; Bridget Candy; Michael King; Irwin Nazareth; Louise Jones; Kirsten Moore Journal: BMC Palliat Care Date: 2019-10-24 Impact factor: 3.234