Literature DB >> 31134755

Adaptive functioning in pediatric brain tumor survivors: An examination of ethnicity and socioeconomic status.

Kimberly P Raghubar1, Jessica Orobio1, M Douglas Ris1, Andrew M Heitzer1, Alexandra Roth1, Austin L Brown2, M Fatih Okcu2, Murali Chintagumpala2, David R Grosshans3, Arnold C Paulino3, Anita Mahajan3, Lisa S Kahalley1.   

Abstract

BACKGROUND: Survivors of pediatric brain tumor are at risk for adaptive difficulties. The present study examined adaptive functioning in a multiethnic sample of survivors accounting for socioeconomic status, and whether demographic, diagnostic, and/or treatment-related variables predict adaptive outcomes.
METHOD: Participants included a multiethnic sample of survivors (58 Caucasian, 34 Hispanic, and 22 other non-Caucasian; M age = 14.05 years, SD = 4.33) who were approximately seven years post-treatment. Parents rated adaptive functioning and provided demographic information. Diagnostic and treatment-related information was abstracted from the electronic medical record.
RESULTS: Parent ratings of adaptive functioning were similar across Caucasian, Hispanic, and other non-Caucasian survivors covarying for family income and primary caregiver education, both of which served as proxies for socioeconomic status. All ethnic groups were rated lower than the normative mean in overall adaptive functioning as well as the specific domains of conceptual, social, and practical skills. Demographic, diagnostic, and treatment-related variables were differentially associated with adaptive functioning in survivors of pediatric brain tumor, though socioeconomic status emerged as a strong significant predictor of adaptive functioning domains.
CONCLUSIONS: Adaptive outcomes do not differ as a function of ethnicity after accounting for primary caregiver education and family income. Racial and ethnic minorities may be at increased risk for poorer outcomes given their overrepresentation at lower income levels. Assessing demographic and treatment-related variables early on may be helpful in identifying children likely to develop adaptive difficulties.
© 2019 Wiley Periodicals, Inc.

Entities:  

Keywords:  adaptive functioning; brain tumor; ethnicity; radiation; socioeconomic status

Mesh:

Year:  2019        PMID: 31134755      PMCID: PMC6730637          DOI: 10.1002/pbc.27800

Source DB:  PubMed          Journal:  Pediatr Blood Cancer        ISSN: 1545-5009            Impact factor:   3.167


  31 in total

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Authors:  Alexandra K Roth; M Douglas Ris; Jessica Orobio; Judy Xue; Anita Mahajan; Arnold C Paulino; David Grosshans; M Fatih Okcu; Murali Chintagumpala; Lisa S Kahalley
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2.  Treatment age and neurocognitive outcomes following proton beam radiotherapy for pediatric low- and intermediate-grade gliomas.

Authors:  Andrew M Heitzer; Lisa S Kahalley; Charles G Minard; Claire Stafford; David R Grosshans; M Fatih Okcu; Kimberly P Raghubar; Marsha Gragert; Mark McCurdy; Emily H Warren; Jocelyn Gomez; M Douglas Ris; Arnold C Paulino; Murali Chintagumpala
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