Literature DB >> 31133466

Microglia and Neutrophils to the Rescue.

Mihaela Gadjeva1.   

Abstract

Invasive candidiasis is a medical condition that is challenging to treat. A recent study (Drummond et al.Nat. Immunol. 2019;20:559-570) reveals new insights into the role of microglia and neutrophils in limiting fungal dissemination to the mouse brain. Gaining knowledge into tissue-specific protection mechanisms may ensure improved prognosis and disease management against fungal infections.
Copyright © 2019 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  fungal infection; innate immunity; microglia; neutrophils

Mesh:

Substances:

Year:  2019        PMID: 31133466      PMCID: PMC6625662          DOI: 10.1016/j.it.2019.05.005

Source DB:  PubMed          Journal:  Trends Immunol        ISSN: 1471-4906            Impact factor:   16.687


  10 in total

1.  Meningeal mast cells affect early T cell central nervous system infiltration and blood-brain barrier integrity through TNF: a role for neutrophil recruitment?

Authors:  Blayne A Sayed; Alison L Christy; Margaret E Walker; Melissa A Brown
Journal:  J Immunol       Date:  2010-05-19       Impact factor: 5.422

2.  Toll-like receptor 1 polymorphisms increase susceptibility to candidemia.

Authors:  Theo S Plantinga; Melissa D Johnson; William K Scott; Esther van de Vosse; Digna R Velez Edwards; P Brian Smith; Barbara D Alexander; John C Yang; Dennis Kremer; Gregory M Laird; Marije Oosting; Leo A B Joosten; Jos W M van der Meer; Jaap T van Dissel; Thomas J Walsh; John R Perfect; Bart Jan Kullberg; Mihai G Netea
Journal:  J Infect Dis       Date:  2012-02-01       Impact factor: 5.226

Review 3.  Myeloid Cells in the Central Nervous System.

Authors:  Jasmin Herz; Anthony J Filiano; Ashtyn Smith; Nir Yogev; Jonathan Kipnis
Journal:  Immunity       Date:  2017-06-20       Impact factor: 31.745

4.  CX3CR1-dependent renal macrophage survival promotes Candida control and host survival.

Authors:  Michail S Lionakis; Muthulekha Swamydas; Brett G Fischer; Theo S Plantinga; Melissa D Johnson; Martin Jaeger; Nathaniel M Green; Andrius Masedunskas; Roberto Weigert; Constantinos Mikelis; Wuzhou Wan; Chyi-Chia Richard Lee; Jean K Lim; Aymeric Rivollier; John C Yang; Greg M Laird; Robert T Wheeler; Barbara D Alexander; John R Perfect; Ji-Liang Gao; Bart-Jan Kullberg; Mihai G Netea; Philip M Murphy
Journal:  J Clin Invest       Date:  2013-11-01       Impact factor: 14.808

Review 5.  Antifungal Innate Immunity: A Perspective from the Last 10 Years.

Authors:  Fabián Salazar; Gordon D Brown
Journal:  J Innate Immun       Date:  2018-05-16       Impact factor: 7.349

6.  Invasive fungal infection and impaired neutrophil killing in human CARD9 deficiency.

Authors:  Agata Drewniak; Roel P Gazendam; Anton T J Tool; Michel van Houdt; Machiel H Jansen; John L van Hamme; Ester M M van Leeuwen; Dirk Roos; Emmanuel Scalais; Carine de Beaufort; Hans Janssen; Timo K van den Berg; Taco W Kuijpers
Journal:  Blood       Date:  2013-01-18       Impact factor: 22.113

7.  CARD9 deficiency and spontaneous central nervous system candidiasis: complete clinical remission with GM-CSF therapy.

Authors:  Christina Gavino; Anthony Cotter; Daniel Lichtenstein; Duncan Lejtenyi; Claude Fortin; Catherine Legault; Najmeh Alirezaie; Jacek Majewski; Donald C Sheppard; Marcel A Behr; William D Foulkes; Donald C Vinh
Journal:  Clin Infect Dis       Date:  2014-04-04       Impact factor: 9.079

8.  Retrospective analysis of mortality and Candida isolates of 75 patients with candidemia: a single hospital experience.

Authors:  Ryuichi Hirano; Yuichi Sakamoto; Kumiko Kudo; Motoki Ohnishi
Journal:  Infect Drug Resist       Date:  2015-07-08       Impact factor: 4.003

9.  CARD9+ microglia promote antifungal immunity via IL-1β- and CXCL1-mediated neutrophil recruitment.

Authors:  Muthulekha Swamydas; Vasileios Oikonomou; Bing Zhai; Rebecca A Drummond; Ivy M Dambuza; Brian C Schaefer; Andrea C Bohrer; Katrin D Mayer-Barber; Sergio A Lira; Yoichiro Iwakura; Scott G Filler; Gordon D Brown; Bernhard Hube; Julian R Naglik; Tobias M Hohl; Michail S Lionakis
Journal:  Nat Immunol       Date:  2019-04-17       Impact factor: 25.606

10.  Candida and host determinants of susceptibility to invasive candidiasis.

Authors:  Michail S Lionakis; Mihai G Netea
Journal:  PLoS Pathog       Date:  2013-01-03       Impact factor: 6.823

  10 in total

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