Allison A Gockley1, Beryl L Manning-Geist2, Adeline A Boatin3, Xiangmei Gu4, Sarah Cohen4. 1. Brigham and Women's Hospital, Division of Gynecologic Oncology, Department of Obstetrics and Gynecology,Harvard Medical School, 75 Francis Street, Boston MA, 02115, USA. Electronic address: agockley@partners.org. 2. Brigham and Women's Hospital, Department of Obstetrics and Gynecology,Harvard Medical School, 75 Francis Street, Boston MA, 02115, USA; Massachusetts General Hospital, Department of Obstetrics and Gynecology, Harvard Medical School, 55 Fruit Street, Yawkey 5, Boston MA, 02114, USA. 3. Massachusetts General Hospital, Department of Obstetrics and Gynecology, Harvard Medical School, 55 Fruit Street, Yawkey 5, Boston MA, 02114, USA. 4. Brigham and Women's Hospital, Division of Minimally Invasive Gynecology, Department of Obstetrics and Gynecology,Harvard Medical School, 75 Francis Street, Boston MA, 02115, USA.
Abstract
OBJECTIVES: This study describes the presentation, clinical characteristics and outcomes of postmenopausal women diagnosed with tubo-ovarian abscesses (TOAs). STUDY DESIGN: All postmenopausal women aged over 50 years presenting to three academic institutions with TOAs between 2007 and 2017 were identified. Patient charts were retrospectively reviewed and clinical variables were extracted. Descriptive statistics were prepared and analyses were performed. MAIN OUTCOME MEASURES: The main outcome measures were complications and rate of malignancy. RESULTS: From 2007-2017, 61 postmenopausal women with TOAs were identified. Their median age was 62 years (range 50-87 years). Many of the women presenting with TOAs had co-morbidities; 34.4% had diverticulosis or diverticulitis and 9.8% had diabetes. Among the 61 women, 19 (31.1%) underwent interventional radiology (IR) drainage. Most postmenopausal women presenting with a TOA underwent surgical intervention (n = 47, 77.1%). Thirty-three (54.1%) women underwent early surgery (within 30 days), and 14 (22.9%) underwent late surgery (after 30 days). Overall, 14 (29.8%) women had either an intra-operative or a post-operative complication. Post-operative complications were more common among women who underwent late surgery than among those who underwent early surgery (35.7% vs 9.1%, P = 0.04). However, there was no difference in the readmission rate within 30 days of surgery (P = 1.0) or in the overall complication rate (P = 0.24) between surgery groups. Eight women (13.1%) had malignancy diagnosed either pre-operatively or at the time of their presentation with a TOA. CONCLUSIONS: Postmenopausal women presenting with TOAs often undergo surgical procedures that have a high rate of complications and may be associated with malignancy.
OBJECTIVES: This study describes the presentation, clinical characteristics and outcomes of postmenopausal women diagnosed with tubo-ovarian abscesses (TOAs). STUDY DESIGN: All postmenopausal women aged over 50 years presenting to three academic institutions with TOAs between 2007 and 2017 were identified. Patient charts were retrospectively reviewed and clinical variables were extracted. Descriptive statistics were prepared and analyses were performed. MAIN OUTCOME MEASURES: The main outcome measures were complications and rate of malignancy. RESULTS: From 2007-2017, 61 postmenopausal women with TOAs were identified. Their median age was 62 years (range 50-87 years). Many of the women presenting with TOAs had co-morbidities; 34.4% had diverticulosis or diverticulitis and 9.8% had diabetes. Among the 61 women, 19 (31.1%) underwent interventional radiology (IR) drainage. Most postmenopausal women presenting with a TOA underwent surgical intervention (n = 47, 77.1%). Thirty-three (54.1%) women underwent early surgery (within 30 days), and 14 (22.9%) underwent late surgery (after 30 days). Overall, 14 (29.8%) women had either an intra-operative or a post-operative complication. Post-operative complications were more common among women who underwent late surgery than among those who underwent early surgery (35.7% vs 9.1%, P = 0.04). However, there was no difference in the readmission rate within 30 days of surgery (P = 1.0) or in the overall complication rate (P = 0.24) between surgery groups. Eight women (13.1%) had malignancy diagnosed either pre-operatively or at the time of their presentation with a TOA. CONCLUSIONS: Postmenopausal women presenting with TOAs often undergo surgical procedures that have a high rate of complications and may be associated with malignancy.