Literature DB >> 3113175

Synaptophysin--an immuno-histochemical marker for childhood neuroblastoma.

M Miettinen, J Rapola.   

Abstract

Synaptophysin, an integral membrane glycoprotein of presynaptic vesicles, was tested as an immuno-histochemical marker for childhood neuroblastoma. Synaptophysin immuno-reactivity was found in all neuroblastomas (6/6), but not in the other small round-cell tumors to be considered in its differential diagnosis. Thus, rhabdomyosarcomas (0/5), lymphomas (0/4), or Ewing's sarcomas (0/2) were negative for synaptophysin. The results suggest that synaptophysin is a useful marker for neuroblastoma, and it should belong to the marker panel used for the differential diagnosis of small round-cell tumors of childhood.

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Year:  1987        PMID： 3113175     DOI： 10.1111/j.1699-0463.1987.tb00026_95a.x

Source DB:  PubMed          Journal:  Acta Pathol Microbiol Immunol Scand A        ISSN： 0108-0164


  8 in total

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Authors:  W M Molenaar; L de Leij; J Q Trojanowski
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2.  Microglial and neural differentiation in human teratomas.

Authors:  T Sangruchi; R A Sobel
Journal:  Acta Neuropathol       Date:  1989       Impact factor: 17.088

3.  The neuroendocrine and neural profiles of neuroblastomas, ganglioneuroblastomas, and ganglioneuromas.

Authors:  W M Molenaar; D L Baker; D Pleasure; V M Lee; J Q Trojanowski
Journal:  Am J Pathol       Date:  1990-02       Impact factor: 4.307

4.  Neuroblastic differentiation potential of the human retinoblastoma cell lines Y-79 and WERI-Rb1 maintained in an organ culture system. An immunohistochemical, electron microscopic, and biochemical study.

Authors:  M M Herman; E Perentes; C D Katsetos; F Darcel; A Frankfurter; V P Collins; L A Donoso; L F Eng; P J Marangos; A F Wiechmann
Journal:  Am J Pathol       Date:  1989-01       Impact factor: 4.307

Review 5.  Clinical significance of serum biomarkers in pediatric solid mediastinal and abdominal tumors.

Authors:  John A Sandoval; Linda H Malkas; Robert J Hickey
Journal:  Int J Mol Sci       Date:  2012-01-20       Impact factor: 6.208

6.  A 3D Bioprinted in vitro Model of Neuroblastoma Recapitulates Dynamic Tumor-Endothelial Cell Interactions Contributing to Solid Tumor Aggressive Behavior.

Authors:  Liqun Ning; Jenny Shim; Martin L Tomov; Rui Liu; Riya Mehta; Andrew Mingee; Boeun Hwang; Linqi Jin; Athanasios Mantalaris; Chunhui Xu; Morteza Mahmoudi; Kelly C Goldsmith; Vahid Serpooshan
Journal:  Adv Sci (Weinh)       Date:  2022-05-29       Impact factor: 17.521

Review 7.  Nerve Density and Neuronal Biomarkers in Cancer.

Authors:  Shahrukh R Ali; Madeleine Jordan; Priyadharsini Nagarajan; Moran Amit
Journal:  Cancers (Basel)       Date:  2022-10-01       Impact factor: 6.575

8.  Small round blue cell tumours: diagnostic and prognostic usefulness of the expression of B7-H3 surface molecule.

Authors:  A Gregorio; M V Corrias; R Castriconi; A Dondero; M Mosconi; C Gambini; A Moretta; L Moretta; C Bottino
Journal:  Histopathology       Date:  2008-07       Impact factor: 5.087
  8 in total

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