Literature DB >> 31131304

Systems Biology approaches to cancer: towards new therapeutical strategies and personalized approaches.

Daniel Remondini1.   

Abstract

Network approaches are ubiquitous, from social and ecological systems up to complex biological processes. In our recently published work we used the network framework for a Systems Medicine approach to multiple cancer types, in order to highlight similitudes and differences that can be exploited to extend existing therapeutical strategies. These approaches shed new light to oncological processes, but allow also to pose "old" questions (like the search for novel drug targets) in a "new" way.

Entities:  

Keywords:  Systems oncology; network theory; personalized medicine

Year:  2019        PMID: 31131304      PMCID: PMC6512913          DOI: 10.1080/23723556.2018.1561118

Source DB:  PubMed          Journal:  Mol Cell Oncol        ISSN: 2372-3556


  5 in total

1.  The BioPlex Network: A Systematic Exploration of the Human Interactome.

Authors:  Edward L Huttlin; Lily Ting; Raphael J Bruckner; Fana Gebreab; Melanie P Gygi; John Szpyt; Stanley Tam; Gabriela Zarraga; Greg Colby; Kurt Baltier; Rui Dong; Virginia Guarani; Laura Pontano Vaites; Alban Ordureau; Ramin Rad; Brian K Erickson; Martin Wühr; Joel Chick; Bo Zhai; Deepak Kolippakkam; Julian Mintseris; Robert A Obar; Tim Harris; Spyros Artavanis-Tsakonas; Mathew E Sowa; Pietro De Camilli; Joao A Paulo; J Wade Harper; Steven P Gygi
Journal:  Cell       Date:  2015-07-16       Impact factor: 41.582

2.  Measures of centrality based on the spectrum of the Laplacian.

Authors:  Scott D Pauls; Daniel Remondini
Journal:  Phys Rev E Stat Nonlin Soft Matter Phys       Date:  2012-06-20

3.  Network Propagation Predicts Drug Synergy in Cancers.

Authors:  Hongyang Li; Tingyang Li; Daniel Quang; Yuanfang Guan
Journal:  Cancer Res       Date:  2018-07-27       Impact factor: 12.701

4.  Weighted multiplex networks.

Authors:  Giulia Menichetti; Daniel Remondini; Pietro Panzarasa; Raúl J Mondragón; Ginestra Bianconi
Journal:  PLoS One       Date:  2014-06-06       Impact factor: 3.240

5.  Network integration of multi-tumour omics data suggests novel targeting strategies.

Authors:  Ítalo Faria do Valle; Giulia Menichetti; Giorgia Simonetti; Samantha Bruno; Isabella Zironi; Danielle Fernandes Durso; José C M Mombach; Giovanni Martinelli; Gastone Castellani; Daniel Remondini
Journal:  Nat Commun       Date:  2018-10-30       Impact factor: 14.919

  5 in total

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