Guillain-Barré syndrome in kappa light chain myeloma.

We have reported a case of Guillain-Barré syndrome developing in a patient with kappa light chain myeloma and acute renal failure. No improvement in acute polyneuritis was observed with serial plasma exchange. At autopsy, peripheral nerves showed no evidence of perivascular lymphocytic infiltration or demyelination, no amyloidosis, and no myelomatous infiltration.