Denise C Vidot1, Chad D Rethorst2, Tom J Carmody2, Mark Stoutenberg3, Robrina Walker2, Tracy L Greer2, Madhukar H Trivedi2. 1. University of Miami School of Nursing and Health Studies, 5030 Brunson Ave., Coral Gables, FL 33146, USA. Electronic address: DVidot@miami.edu. 2. The University of Texas Southwestern Medical Center, Department of Psychiatry, 5323 Harry Hines Blvd., Dallas, TX 75290, USA. 3. University of Tennessee at Chattanooga, 615 McCallie Ave., Chattanooga, TN 37403, USA.
Abstract
AIMS: The aim of this study was to examine the impact of vigorous intensity, high dose exercise (DEI) on cannabis use among stimulant users compared to a health education intervention (HEI) using data from the Stimulant Reduction Intervention using Dosed Exercise, National Institute of Drug Abuse National Drug Treatment Clinical Trials Network Protocol Number 0037 (STRIDE). METHODS: Adults (N = 302) enrolled in the STRIDE randomized clinical trial were randomized to either the DEI or the HEI. Interventions included supervised sessions three times a week during the Acute phase (12 weeks) and once a week during the Follow-up phase (6 months). Cannabis use was measured at each assessment via Timeline Follow Back and urine drug screens. Cannabis use was compared between the groups during the Acute and Follow-up phases using both the intent-to-treat sample and a complier average causal effects (CACE) analysis. FINDINGS: Approximately 43% of the sample reported cannabis use at baseline. The difference in cannabis use between the DEI and HEI groups during the Acute phase was not significant. During the Follow-up phase, the days of cannabis use was significantly lower among those in the DEI group (1.20 days) compared to the HEI group (2.15 days; p = 0.04). CONCLUSIONS: For those who adhered to the exercise intervention, vigorous intensity, high dose exercise resulted in less cannabis use. Results suggest that there were no significant short-term differences in cannabis use between the groups. Further study on the long-term impact of exercise as a treatment to reduce cannabis use should be considered.
RCT Entities:
AIMS: The aim of this study was to examine the impact of vigorous intensity, high dose exercise (DEI) on cannabis use among stimulant users compared to a health education intervention (HEI) using data from the Stimulant Reduction Intervention using Dosed Exercise, National Institute of Drug Abuse National Drug Treatment Clinical Trials Network Protocol Number 0037 (STRIDE). METHODS: Adults (N = 302) enrolled in the STRIDE randomized clinical trial were randomized to either the DEI or the HEI. Interventions included supervised sessions three times a week during the Acute phase (12 weeks) and once a week during the Follow-up phase (6 months). Cannabis use was measured at each assessment via Timeline Follow Back and urine drug screens. Cannabis use was compared between the groups during the Acute and Follow-up phases using both the intent-to-treat sample and a complier average causal effects (CACE) analysis. FINDINGS: Approximately 43% of the sample reported cannabis use at baseline. The difference in cannabis use between the DEI and HEI groups during the Acute phase was not significant. During the Follow-up phase, the days of cannabis use was significantly lower among those in the DEI group (1.20 days) compared to the HEI group (2.15 days; p = 0.04). CONCLUSIONS: For those who adhered to the exercise intervention, vigorous intensity, high dose exercise resulted in less cannabis use. Results suggest that there were no significant short-term differences in cannabis use between the groups. Further study on the long-term impact of exercise as a treatment to reduce cannabis use should be considered.
Authors: Bess H Marcus; Beth A Lewis; Joseph Hogan; Teresa K King; Anna E Albrecht; Beth Bock; Alfred F Parisi; Raymond Niaura; David B Abrams Journal: Nicotine Tob Res Date: 2005-12 Impact factor: 4.244
Authors: Katherine Sanchez; Karen G Chartier; Tracy L Greer; Robrina Walker; Thomas Carmody; Chad D Rethorst; Kolette M Ring; Adriane M Dela Cruz; Madhukar H Trivedi Journal: J Ethn Subst Abuse Date: 2015-01-12 Impact factor: 1.507
Authors: Chad D Rethorst; Tracy L Greer; Bruce Grannemann; Kolette M Ring; Bess H Marcus; Madhukar H Trivedi Journal: Ment Health Phys Act Date: 2014-03-01
Authors: Mark Stoutenberg; Chad Rethorst; Gabriel Fuzat; Tracy Greer; Steven Blair; Timothy Church; Bess Marcus; Madhukar Trivedi Journal: Ment Health Phys Act Date: 2012-12