Binny Thomas1,2, Vibhu Paudyal3, Katie MacLure2, Abdulrouf Pallivalapila1, James McLay4, Wessam El Kassem1, Moza Al Hail1, Derek Stewart5. 1. Medication Safety and Quality Center, Pharmacy Executive Office, Hamad Medical Corporation, PO Box 3050, Doha, Qatar. 2. School of Pharmacy and Life Sciences, Robert Gordon University, Aberdeen, AB10 7JG, UK. 3. School of Pharmacy, University of Birmingham, Birmingham, B15 2TT, UK. 4. The Institute of Applied Health Sciences, University of Aberdeen, Aberdeen, AB25 2ZD, UK. 5. College of Pharmacy, Qatar University, Doha, PO Box 2713, Qatar. d.stewart@rgu.ac.uk.
Abstract
PURPOSE: The aim was to critically appraise, synthesise and present the evidence of medication errors amongst hospitalised patients in Middle Eastern countries, specifically prevalence, nature, severity and contributory factors. METHODS: CINAHL, Embase, Medline, Pubmed and Science Direct were searched for studies published in English from 2000 to March 2018, with no exclusions. Study selection, quality assessment (using adapted STROBE checklists) and data extraction were conducted independently by two reviewers. A narrative approach to data synthesis was adopted; data related to error causation were synthesised according to Reason's Accident Causation model. RESULTS: Searching yielded 452 articles, which were reduced to 50 following removal of duplicates and screening of titles, abstracts and full-papers. Studies were largely from Iran, Saudi Arabia, Egypt and Jordan. Thirty-two studies quantified errors; definitions of 'medication error' were inconsistent as were approaches to data collection, severity assessment, outcome measures and analysis. Of 13 studies reporting medication errors per 'total number of medication orders'/ 'number of prescriptions', the median across all studies was 10% (IQR 2-35). Twenty-four studies reported contributory factors leading to errors. Synthesis according to Reason's model identified the most common being active failures, largely slips (10 studies); lapses (9) and mistakes (12); error-provoking conditions, particularly lack of knowledge (13) and insufficient staffing levels (13) and latent conditions, commonly heavy workload (9). CONCLUSION: There is a need to improve the quality and reporting of studies from Middle Eastern countries. A standardised approach to quantifying medication errors' prevalence, severity, outcomes and contributory factors is warranted.
PURPOSE: The aim was to critically appraise, synthesise and present the evidence of medication errors amongst hospitalised patients in Middle Eastern countries, specifically prevalence, nature, severity and contributory factors. METHODS: CINAHL, Embase, Medline, Pubmed and Science Direct were searched for studies published in English from 2000 to March 2018, with no exclusions. Study selection, quality assessment (using adapted STROBE checklists) and data extraction were conducted independently by two reviewers. A narrative approach to data synthesis was adopted; data related to error causation were synthesised according to Reason's Accident Causation model. RESULTS: Searching yielded 452 articles, which were reduced to 50 following removal of duplicates and screening of titles, abstracts and full-papers. Studies were largely from Iran, Saudi Arabia, Egypt and Jordan. Thirty-two studies quantified errors; definitions of 'medication error' were inconsistent as were approaches to data collection, severity assessment, outcome measures and analysis. Of 13 studies reporting medication errors per 'total number of medication orders'/ 'number of prescriptions', the median across all studies was 10% (IQR 2-35). Twenty-four studies reported contributory factors leading to errors. Synthesis according to Reason's model identified the most common being active failures, largely slips (10 studies); lapses (9) and mistakes (12); error-provoking conditions, particularly lack of knowledge (13) and insufficient staffing levels (13) and latent conditions, commonly heavy workload (9). CONCLUSION: There is a need to improve the quality and reporting of studies from Middle Eastern countries. A standardised approach to quantifying medication errors' prevalence, severity, outcomes and contributory factors is warranted.
Authors: Josephine Henry Basil; Chandini Menon Premakumar; Adliah Mhd Ali; Nurul Ain Mohd Tahir; Noraida Mohamed Shah Journal: Drug Saf Date: 2022-10-03 Impact factor: 5.228
Authors: Francisco Miguel Escandell-Rico; Juana Perpiñá-Galvañ; Lucía Pérez-Fernández; Ángela Sanjuán-Quiles; Piedras Albas Gómez-Beltrán; Juan Diego Ramos-Pichardo Journal: Int J Environ Res Public Health Date: 2021-04-02 Impact factor: 3.390
Authors: Abdulrhman Al Rowily; Zahraa Jalal; Malcolm J Price; Mohammed H Abutaleb; Hind Almodiaemgh; Maha Al Ammari; Vibhu Paudyal Journal: Eur J Clin Pharmacol Date: 2021-12-22 Impact factor: 2.953