Literature DB >> 3112717

Diabetic ketoacidosis. Biochemistry, physiology, treatment, and prevention.

E J Krane.   

Abstract

Diabetic ketoacidosis (DKA) is the most common cause of death of juvenile-onset diabetics, and as such represents an important issue for pediatricians. In this article, the author reviews the endocrinology of insulin and the glucose counter-regulatory hormones, which are the basis for the development of DKA. The effects of hyperglycemia and acidosis upon organ physiology are detailed, and this serves as the foundation for subsequent discussion of the management of the patient with DKA. Finally, the author summarizes current strategies for prevention of DKA in patients with diabetes.

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Year:  1987        PMID： 3112717     DOI： 10.1016/s0031-3955(16)36296-4

Source DB:  PubMed          Journal:  Pediatr Clin North Am        ISSN： 0031-3955            Impact factor:   3.278


  6 in total

1.  Acetate represents a major product of heptanoate and octanoate beta-oxidation in hepatocytes isolated from neonatal piglets.

Authors:  X Lin; S H Adams; J Odle
Journal:  Biochem J       Date:  1996-08-15       Impact factor: 3.857

2.  Ketoacidosis at the diagnosis of type 1 (insulin dependent) diabetes mellitus is related to poor residual beta cell function. Childhood Diabetes in Finland Study Group.

Authors:  J Komulainen; R Lounamaa; M Knip; E A Kaprio; H K Akerblom
Journal:  Arch Dis Child       Date:  1996-11       Impact factor: 3.791

Review 3.  Diabetes in infancy: diagnosis and current management.

Authors:  G L Bland; V D Wood
Journal:  J Natl Med Assoc       Date:  1991-04       Impact factor: 1.798

Review 4.  Cell volume regulation: a review of cerebral adaptive mechanisms and implications for clinical treatment of osmolal disturbances: II.

Authors:  H Trachtman
Journal:  Pediatr Nephrol       Date:  1992-01       Impact factor: 3.714

Review 5.  Hyperketonemia and ketosis increase the risk of complications in type 1 diabetes.

Authors:  Preeti Kanikarla-Marie; Sushil K Jain
Journal:  Free Radic Biol Med       Date:  2016-03-29       Impact factor: 7.376

6.  Anti-hyperglycemic and ameliorative effect of concentrated hot water-infusion of Phragmanthera incana leaves on type 2 diabetes and indices of complications in diabetic rats.

Authors:  Olakunle Sanni; Ochuko L Erukainure; Olajumoke Oyebode; Md Shahidul Islam
Journal:  J Diabetes Metab Disord       Date:  2019-11-14
  6 in total

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