Hee-Young Kang1, Eun-Young Choi2. 1. a Department of Nursing, Chosun University , 309, Pilmundaero, Dong-gu, Gwangju 61452 , South Korea. 2. b Department of Nursing, Chosun Nursing College , 309-2, Pilmundaero, Dong-gu, Gwangju 61453 , South Korea.
Abstract
Background: Over the course of repetitive and long-term chemotherapy treatment, multiple myeloma (MM) patients experience physical and psychological problems and side effects. Objectives: The objective of this study was to investigate the levels of pain, uncertainty, social support, anxiety, depression, and quality of life (QOL) receiving chemotherapy for MM patients and to identify psychosocial factors influencing their QOL. Methods: A cross-sectional descriptive design was used. A total of 110 MM patients receiving chemotherapy were recruited into the study. The data were collected by personal interviews using questionnaires and were analyzed using descriptive statistics, t-test, one-way ANOVA, Pearson's correlation, and hierachial multiple regression analysis. Findings: Global health status QOL was explained by uncertainty, anxiety, and depression. Functional QOL was explained by age, uncertainty, and anxiety. Symptom QOL was explained by pain, and depression. Uncertainty, anxiety and depression were the strongest predictive factors. To improve QOL of patients with MM, nurses should focus on the factors identified in this study when doing nursing care. Impact statement: This study confirmed psychological difficulties such as uncertainty, anxiety and depression affecting quality of life of MM patients receiving chemotherapy.
Background: Over the course of repetitive and long-term chemotherapy treatment, multiple myeloma (MM) patients experience physical and psychological problems and side effects. Objectives: The objective of this study was to investigate the levels of pain, uncertainty, social support, anxiety, depression, and quality of life (QOL) receiving chemotherapy for MMpatients and to identify psychosocial factors influencing their QOL. Methods: A cross-sectional descriptive design was used. A total of 110 MMpatients receiving chemotherapy were recruited into the study. The data were collected by personal interviews using questionnaires and were analyzed using descriptive statistics, t-test, one-way ANOVA, Pearson's correlation, and hierachial multiple regression analysis. Findings: Global health status QOL was explained by uncertainty, anxiety, and depression. Functional QOL was explained by age, uncertainty, and anxiety. Symptom QOL was explained by pain, and depression. Uncertainty, anxiety and depression were the strongest predictive factors. To improve QOL of patients with MM, nurses should focus on the factors identified in this study when doing nursing care. Impact statement: This study confirmed psychological difficulties such as uncertainty, anxiety and depression affecting quality of life of MMpatients receiving chemotherapy.
Entities:
Keywords:
anxiety; depression; multiple myeloma; quality of life; uncertainty
Authors: Ademola S Ojo; Somtochukwu G Ojukwu; Joseph Asemota; Oluwasegun Akinyemi; Mojisola O Araoye; Mohammed Saleh; Ahmed Ali; Ravi Sarma Journal: J Cancer Res Clin Oncol Date: 2022-01-20 Impact factor: 4.553