| Literature DB >> 31122309 |
Zarui A Melikyan1, Maria M Corrada1, Malcolm B Dick1, Christina Whittle1, Annlia Paganini-Hill2, Claudia H Kawas1.
Abstract
OBJECTIVES: Individuals aged 90 or older (oldest-old), the fastest growing segment of the population, are at increased risk of developing cognitive impairment compared with younger old. Neuropsychological evaluation of the oldest-old is important yet challenging in part because of the scarcity of test norms for this group. We provide neuropsychological test norms for cognitively intact oldest-old. <br> METHODS: Test norms were derived from 403 cognitively intact participants of The 90+ Study, an ongoing study of aging and dementia in the oldest-old. Cognitive status of intact oldest-old was determined at baseline using cross-sectional approach. Individuals with cognitive impairment no dementia or dementia (according to DSM-IV criteria) were excluded. Participants ranged in age from 90 to 102 years (mean=94). The neuropsychological battery included 11 tests (Mini-Mental Status Examination, Modified Mini-Mental State Examination, Boston Naming Test - Short Form, Letter Fluency Test, Animal Fluency Test, California Verbal Learning Test-II Short Form, Trail Making Tests A/B/C, Digit Span Forward and Backwards Test, Clock Drawing Test, CERAD Construction Subtests), and the Geriatric Depression Scale. <br> RESULTS: Data show significantly lower scores with increasing age on most tests. Education level, sex, and symptoms of depression were associated with performance on several tests after accounting for age. <br> CONCLUSIONS: Provided test norms will help to distinguish cognitively intact oldest-old from those with cognitive impairment. (JINS, 2019, 25, 530-545).Entities:
Keywords: 80 and over; Aged; Cognition; Geriatric assessment; Neuropsychology; Reference values
Year: 2019 PMID: 31122309 PMCID: PMC6538395 DOI: 10.1017/S1355617719000122
Source DB: PubMed Journal: J Int Neuropsychol Soc ISSN: 1355-6177 Impact factor: 2.892