Literature DB >> 31121127

Huntingtin Lowering Strategies for Disease Modification in Huntington's Disease.

Sarah J Tabrizi, Rhia Ghosh, Blair R Leavitt.   

Abstract

Entities:  

Year:  2019        PMID： 31121127     DOI： 10.1016/j.neuron.2019.05.001

Source DB:  PubMed          Journal:  Neuron        ISSN： 0896-6273            Impact factor:   17.173


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  11 in total

Review 1.  Therapeutic Update on Huntington's Disease: Symptomatic Treatments and Emerging Disease-Modifying Therapies.

Authors:  Deepa Dash; Tiago A Mestre
Journal:  Neurotherapeutics       Date:  2020-10       Impact factor: 7.620

Review 2.  CRISPR-Cas9-Mediated Gene Therapy in Neurological Disorders.

Authors:  Lihong Guan; Yawei Han; Ciqing Yang; Suxiang Lu; Jiang Du; Han Li; Juntang Lin
Journal:  Mol Neurobiol       Date:  2021-11-23       Impact factor: 5.590

Review 3.  Autophagy in health and disease: From molecular mechanisms to therapeutic target.

Authors:  Guang Lu; Yu Wang; Yin Shi; Zhe Zhang; Canhua Huang; Weifeng He; Chuang Wang; Han-Ming Shen
Journal:  MedComm (2020)       Date:  2022-07-10

4.  Biodistribution and dosimetry in human healthy volunteers of the PET radioligands [11C]CHDI-00485180-R and [11C]CHDI-00485626, designed for quantification of cerebral aggregated mutant huntingtin.

Authors:  Aline Delva; Michel Koole; Wim Vandenberghe; Koen Van Laere; Kim Serdons; Guy Bormans; Longbin Liu; Jonathan Bard; Vinod Khetarpal; Celia Dominguez; Ignacio Munoz-Sanjuan; Andrew Wood; Mette Skinbjerg; Yuchuan Wang
Journal:  Eur J Nucl Med Mol Imaging       Date:  2022-08-24       Impact factor: 10.057

5.  Suppression of toxicity of the mutant huntingtin protein by its interacting compound, desonide.

Authors:  Haikun Song; Cen Wang; Chenggang Zhu; Ziying Wang; Huiya Yang; Peng Wu; Xiaotian Cui; Juan Botas; Yongjun Dang; Yu Ding; Yiyan Fei; Boxun Lu
Journal:  Proc Natl Acad Sci U S A       Date:  2022-03-01       Impact factor: 12.779

6.  HuR stabilizes HTT mRNA via interacting with its exon 11 in a mutant HTT-dependent manner.

Authors:  Quan Zhao; Chen Li; Meng Yu; Yimin Sun; Jian Wang; Lixiang Ma; Xiaoli Sun; Boxun Lu
Journal:  RNA Biol       Date:  2020-01-13       Impact factor: 4.652

7.  Cognitive decline in Huntington's disease in the Digitalized Arithmetic Task (DAT).

Authors:  Marine Lunven; Jennifer Hamet Bagnou; Katia Youssov; Alexis Gabadinho; Rafika Fliss; Justine Montillot; Etienne Audureau; Blanche Bapst; Graça Morgado; Ralf Reilmann; Robin Schubert; Monica Busse; David Craufurd; Renaud Massart; Anne Rosser; Anne-Catherine Bachoud-Lévi
Journal:  PLoS One       Date:  2021-08-23       Impact factor: 3.240

8.  Nemo-like kinase reduces mutant huntingtin levels and mitigates Huntington's disease.

Authors:  Mali Jiang; Xiaoyan Zhang; Hongshuai Liu; Jared LeBron; Athanasios Alexandris; Qi Peng; Hao Gu; Fanghan Yang; Yuchen Li; Ruiling Wang; Zhipeng Hou; Nicolas Arbez; Qianwei Ren; Jen-Li Dong; Emma Whela; Ronald Wang; Tamara Ratovitski; Juan C Troncoso; Susumu Mori; Christopher A Ross; Janghoo Lim; Wenzhen Duan
Journal:  Hum Mol Genet       Date:  2020-05-28       Impact factor: 6.150

9.  Wild-type huntingtin regulates human macrophage function.

Authors:  Grace C O'Regan; Sahar H Farag; Gary R Ostroff; Sarah J Tabrizi; Ralph Andre
Journal:  Sci Rep       Date:  2020-10-14       Impact factor: 4.379

Review 10.  Huntington disease: new insights into molecular pathogenesis and therapeutic opportunities.

Authors:  Sarah J Tabrizi; Michael D Flower; Christopher A Ross; Edward J Wild
Journal:  Nat Rev Neurol       Date:  2020-08-14       Impact factor: 42.937
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