| Literature DB >> 311204 |
A J Swaak, L A Aarden, L W Statius van Eps, T E Feltkamp.
Abstract
Antibodies to dsDNA, tested with circular DNA in the Farr assay, are specific for systemic lupus erythematosus. A longitudinal study showed a clear relation between the clinical state, the anti-dsDNA titer (expressed in units), and the C1q and C3 levels: when anti-dsDNA levels remained high, no exacerbations were observed. A sharp drop in anti-dsDNA, usually preceded by a rise, was related to a serious exacerbation. Only during the exacerbation when both C1q and C3 were very low was renal involvement seen.Entities:
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Year: 1979 PMID： 311204 DOI： 10.1002/art.1780220304
Source DB: PubMed Journal: Arthritis Rheum ISSN： 0004-3591