Literature DB >> 3112024

[Use of pseudomonas immunoglobulin in ventilated patients at an interdisciplinary surgical intensive care station].

I Class, W Junginger, T Klöss.   

Abstract

The clinical efficacy and safety of a new pseudomonas hyperimmune globulin for intravenous administration were examined in 30 patients in a prospective randomized study. Although the statistical evaluation of the measurable parameters did not show relevant differences between the therapy group (n = 15) and the controls (n = 15), the clinical course of the disease was markedly better in patients treated with hyperimmune globulin. In the control group, three patients died from Pseudomonas aeruginosa infections, but none in the therapy group. The preparation was very well tolerated.

Entities:  

Mesh:

Substances:

Year:  1987        PMID: 3112024     DOI: 10.1007/bf01644196

Source DB:  PubMed          Journal:  Infection        ISSN: 0300-8126            Impact factor:   3.553


  7 in total

Review 1.  Pseudomonas aeruginosa: clinical manifestations and management.

Authors:  I M Gould; R Wise
Journal:  Lancet       Date:  1985-11-30       Impact factor: 79.321

2.  Experimental studies of the pathogenesis of infections due to Pseudomonas aeruginosa. Treatment with intravenous immune globulin.

Authors:  I A Holder; J G Naglich
Journal:  Am J Med       Date:  1984-03-30       Impact factor: 4.965

3.  Exotoxin production by clinical isolates of pseudomonas aeruginosa.

Authors:  M Pollack; N S Taylor; L T Callahan
Journal:  Infect Immun       Date:  1977-03       Impact factor: 3.441

4.  Protective activity of antibodies to exotoxin A and lipopolysaccharide at the onset of Pseudomonas aeruginosa septicemia in man.

Authors:  M Pollack; L S Young
Journal:  J Clin Invest       Date:  1979-02       Impact factor: 14.808

5.  Infections during intensive chemotherapy for non-Hodgkin's lymphoma.

Authors:  J F Bishop; S C Schimpff; C H Diggs; P H Wiernik
Journal:  Ann Intern Med       Date:  1981-11       Impact factor: 25.391

6.  Preliminary study on administration of high-titer lipid A antibody serum in sepsis and septic shock patients.

Authors:  W Marget; P J Mar; L Jaspers; K Possinger; H Haslberger
Journal:  Infection       Date:  1985 May-Jun       Impact factor: 3.553

7.  Evidence for the role of toxin A in the pathogenesis of infection with Pseudomonas aeruginosa in humans.

Authors:  A S Cross; J C Sadoff; B H Iglewski; P A Sokol
Journal:  J Infect Dis       Date:  1980-10       Impact factor: 5.226

  7 in total
  3 in total

Review 1.  Immunological perspectives in prevention and treatment of nosocomial pneumonia.

Authors:  J E Pennington
Journal:  Intensive Care Med       Date:  1992       Impact factor: 17.440

2.  Pseudomonas aeruginosa immunotherapy.

Authors:  J E Pennington
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1990-06       Impact factor: 3.267

3.  Supplemental immunoglobulin (ivIgG) treatment in 163 patients with sepsis and septic shock--an observational study as a prerequisite for placebo-controlled clinical trials.

Authors:  G Pilz; S Kääb; G Neeser; I Class; U Schweigart; A Brähler; O Bujdoso; R Neumann; K Werdan
Journal:  Infection       Date:  1991 Jul-Aug       Impact factor: 3.553

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.