| Literature DB >> 31118481 |
Amit Raj Sharma1, Tao Zhou1, Enjuro Harunari1, Naoya Oku1, Agus Trianto2, Yasuhiro Igarashi3.
Abstract
A new catecholate-containing siderophore, labrenzbactin (1), was isolated from the fermentation broth of a coral-associated bacterium Labrenzia sp. The structure and absolute configuration of 1 was determined by spectroscopic methods and Marfey's analysis. Overall, 1 showed antimicrobial activity against Ralstonia solanacearum SUPP1541 and Micrococcus luteus ATCC9341 with MIC values of 25 and 50 µg ml-1, respectively, and cytotoxicity against P388 murine leukemia cells with an IC50 of 13 µM.Entities:
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Year: 2019 PMID: 31118481 DOI: 10.1038/s41429-019-0192-x
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN: 0021-8820 Impact factor: 2.649