Literature DB >> 31117715

Carbene-Catalyzed α-Carbon Amination of Chloroaldehydes for Enantioselective Access to Dihydroquinoxaline Derivatives.

Ruoyan Huang1, Xingkuan Chen2, Chengli Mou3, Guoyong Luo3, Yongjia Li2, Xiangyang Li1, Wei Xue1, Zhichao Jin1, Yonggui Robin Chi1,2.   

Abstract

An NHC-catalyzed α-carbon amination of chloroaldehydes was developed. Cyclohexadiene-1,2-diimines are used as amination reagents and four-atom synthons. Our reaction affords optically enriched dihydroquinoxalines that are core structures in natural products and synthetic bioactive molecules.

Entities:  

Year:  2019        PMID： 31117715     DOI： 10.1021/acs.orglett.9b01520

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

Review 1.  Acyclic Twisted Amides.

Authors:  Guangrong Meng; Jin Zhang; Michal Szostak
Journal:  Chem Rev       Date:  2021-08-18       Impact factor: 72.087

Review 2.  Recent advances of N-heterocyclic carbenes in the applications of constructing carbo- and heterocyclic frameworks with potential biological activity.

Authors:  Mei-Mei Li; Xiaozhen Chen; Yun Deng; Jun Lu
Journal:  RSC Adv       Date:  2021-11-26       Impact factor: 4.036

3.  Supported Gold Nanoparticle-Catalyzed Selective Reduction of Multifunctional, Aromatic Nitro Precursors into Amines and Synthesis of 3,4-Dihydroquinoxalin-2-Ones.

Authors:  Domna Iordanidou; Michael G Kallitsakis; Marina A Tzani; Dimitris I Ioannou; Tryfon Zarganes-Tzitzikas; Constantinos G Neochoritis; Alexander Dömling; Michael A Terzidis; Ioannis N Lykakis
Journal:  Molecules       Date:  2022-07-08       Impact factor: 4.927

Review 4.  Diaza-1,3-butadienes as Useful Intermediate in Heterocycles Synthesis.

Authors:  Jorge Heredia-Moya; Daniel A Zurita; José Eduardo Cadena-Cruz; Christian D Alcívar-León
Journal:  Molecules       Date:  2022-10-09       Impact factor: 4.927
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.