Literature DB >> 31117522

Cytotoxic Tigliane Diterpenoids from Croton damayeshu.

Jiao-Jiao Cui1,2, Kai-Long Ji1, Hong-Chun Liu1, Bin Zhou1, Qun-Fang Liu1, Cheng-Hui Xu1, Jian Ding1, Jin-Xin Zhao1, Jian-Min Yue1,2.   

Abstract

Chemical investigation of an EtOH extract of the twigs and leaves of Croton damayeshu afforded 10 new tigliane diterpenoids, crodamoids A-J (1-10), along with five known compounds. Their structures were elucidated by physical data analysis. Compounds 8, 9, and 15 displayed cytotoxic effects against two human tumor cell lines, A549 and HL-60 (IC50: 0.9-2.4 μM).

Entities:  

Year:  2019        PMID： 31117522     DOI： 10.1021/acs.jnatprod.9b00042

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  3 in total

Review 1.  New Diterpenes with Potential Antitumoral Activity Isolated from Plants in the Years 2017-2022.

Authors:  Cristina Forzato; Patrizia Nitti
Journal:  Plants (Basel)       Date:  2022-08-29

2.  Diterpenoids and C13 Nor-Isoprenoid Identified From the Leaves and Twigs of Croton yanhuii Activating Apoptosis and Pyroptosis.

Authors:  Yue-Qian Li; Bo-Lin Hou; Mei-Jie Wang; Ru-Yue Wang; Xiao-Han Chen; Xu Liu; Dong-Qing Fei; Zhan-Xin Zhang; Er-Wei Li
Journal:  Front Chem       Date:  2022-03-28       Impact factor: 5.221

3.  Croargoids A-G, Eudesmane Sesquiterpenes from the Bark of Croton argyratus.

Authors:  Min Wu; Kai-Long Ji; Peng Sun; Jian-Mei Lu; Jia-Rui Yue; Dong-Hua Cao; Chun-Fen Xiao; You-Kai Xu
Journal:  Molecules       Date:  2022-09-27       Impact factor: 4.927
  3 in total

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