Yunsoo Soh1, Jong Ha Lee1, Junyang Jung2, Sung Hwa Dong3, Jae Yong Byun3, Moon Suh Park3, Sang Hoon Kim3, Seung Geun Yeo4. 1. Department of Rehabilitation Medicine, KyungHee University Hospital, Seoul, Republic of Korea. 2. Department of Anatomy, School of Medicine, Kyung Hee University, Seoul, Republic of Korea. 3. Department of Otolaryngology, Head and Neck Surgery, Graduate School, Kyung Hee University, Seoul, Republic of Korea. 4. Department of Otolaryngology, Head and Neck Surgery, Graduate School, Kyung Hee University, Seoul, Republic of Korea, yeo2park@gmail.com.
Abstract
BACKGROUND: Prediction of the severity and outcomes of Ramsay Hunt syndrome (RHS) is difficult. OBJECTIVES: The aim of this study was to evaluate the predictive power of the neutrophil-to-lymphocyte ratio (NLR) for the severity and outcomes of RHS. MATERIAL AND METHODS: From 2007 to 2017, a retrospective study of 102 hospitalized patients with RHS was conducted. The degree of paralysis was assessed by determining the House-Brackmann (H-B) grade. Obesity, hypertension, and diabetes mellitus were assessed, and the blood NLR and platelet-to-lymphocyte ratio were determined. The patients received steroids and antivirals, and were followed in the outpatient department at 1, 4, 12, and 24 weeks. RESULTS: The H-B grade of the high-NLR group was significantly higher than that of the normal-NLR group (p = 0.039), and the probability of complete recovery was significantly lower in the high-NLR group (p = 0.048). CONCLUSIONS: Patients with RHS who have an elevated NLR have poor outcomes in terms of the H-B grade. Therefore, the NLR may be useful for evaluating the prognosis of patients with RHS.
BACKGROUND: Prediction of the severity and outcomes of Ramsay Hunt syndrome (RHS) is difficult. OBJECTIVES: The aim of this study was to evaluate the predictive power of the neutrophil-to-lymphocyte ratio (NLR) for the severity and outcomes of RHS. MATERIAL AND METHODS: From 2007 to 2017, a retrospective study of 102 hospitalized patients with RHS was conducted. The degree of paralysis was assessed by determining the House-Brackmann (H-B) grade. Obesity, hypertension, and diabetes mellitus were assessed, and the blood NLR and platelet-to-lymphocyte ratio were determined. The patients received steroids and antivirals, and were followed in the outpatient department at 1, 4, 12, and 24 weeks. RESULTS: The H-B grade of the high-NLR group was significantly higher than that of the normal-NLR group (p = 0.039), and the probability of complete recovery was significantly lower in the high-NLR group (p = 0.048). CONCLUSIONS:Patients with RHS who have an elevated NLR have poor outcomes in terms of the H-B grade. Therefore, the NLR may be useful for evaluating the prognosis of patients with RHS.