| Literature DB >> 31115307 |
Alexandra Tejada-Strop1, Rania A Tohme1, Jocelyne Andre-Alboth2, Lana Childs3,1, Xin Ji1, Vivianne de Oliveira Landgraf de Castro4, Jacques Boncy2, Saleem Kamili1.
Abstract
Hepatitis E virus (HEV) infection is associated with a high fatality rate among pregnant women, and gestational complications have been reported among pregnant women infected with hepatitis A virus (HAV). The aim of this study was to determine the seroprevalence of HAV and HEV infections among pregnant women in Haiti. We stratified the population (n = 1,307) between West and non-West regions. Specimens were tested for total HAV antibody (anti-HAV), and IgM and IgG HEV antibody (anti-HEV). Overall, 96.8% pregnant women were positive for total anti-HAV, 10.3% for IgG anti-HEV, and 0.3% for IgM anti-HEV. The prevalence of IgG anti-HEV in the non-West region (12.3%) was significantly greater than that in the West region (5.3%) (P < 0.0001). Most pregnant women in Haiti had evidence of past exposure and immunity to HAV. The non-West region had a higher prevalence of HEV. Improvement in water and sanitation will help in the prevention and control of these infections in Haiti.Entities:
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Year: 2019 PMID： 31115307 PMCID： PMC6609209 DOI： 10.4269/ajtmh.19-0020
Source DB: PubMed Journal: Am J Trop Med Hyg ISSN： 0002-9637 Impact factor: 2.345