Literature DB >> 31111297

Relationship Type and Use of the Vaginal Ring for HIV-1 Prevention in the MTN 020/ASPIRE Trial.

E Pleasants1, T Tauya2, K Reddy3, B G Mirembe4, K Woeber5, T Palanee-Phillips3, C Zimba6,7, M Atujuna8, E T Montgomery9.   

Abstract

Gender roles and imbalances in sexual power contribute to the heightened HIV-1 risk faced by women in Sub-Saharan Africa. This has led prevention research to focus on the development of female controlled methods. Despite the design of products such as vaginal rings to be used autonomously by women, male partners and women's perceptions of relationships influence HIV prevention choices. To understand the influences that male partners and dyadic dynamics had on the use of the Dapivirine Vaginal Ring in the ASPIRE trial, this analysis of qualitative data explored the types of intimate partner relationships that women engaged in. This paper describes how partners facilitated or challenged women's ring use and how women dealt with these challenges within six different types of relationships characterized by power dynamics and commitment levels. We offer insights into how future use of female-initiated HIV prevention products can be promoted through recognition of different relationship types.

Entities:  

Keywords:  Adherence; Clinical trial; Couples; Female controlled HIV prevention; Gender; Gender relations; HIV; Microbicide; Qualitative research; Sexual relationship; Sub-Saharan Africa; Vaginal ring; Women

Mesh:

Substances:

Year:  2020        PMID: 31111297      PMCID: PMC6864230          DOI: 10.1007/s10461-019-02521-9

Source DB:  PubMed          Journal:  AIDS Behav        ISSN: 1090-7165


  46 in total

1.  High acceptability of a vaginal ring intended as a microbicide delivery method for HIV prevention in African women.

Authors:  A van der Straten; E T Montgomery; H Cheng; L Wegner; G Masenga; C von Mollendorf; L Bekker; S Ganesh; K Young; J Romano; A Nel; C Woodsong
Journal:  AIDS Behav       Date:  2012-10

2.  Gender role and relationship norms among young adults in South Africa: measuring the context of masculinity and HIV risk.

Authors:  Abigail Harrison; Lucia F O'Sullivan; Susie Hoffman; Curtis Dolezal; Robert Morrell
Journal:  J Urban Health       Date:  2006-07       Impact factor: 3.671

Review 3.  Cultural politics and masculinities: multiple-partners in historical perspective in KwaZulu-Natal.

Authors:  Mark Hunter
Journal:  Cult Health Sex       Date:  2005-05

4.  'If I buy the Kellogg's then he should [buy] the milk': young women's perspectives on relationship dynamics, gender power and HIV risk in Johannesburg, South Africa.

Authors:  Audrey Pettifor; Catherine Macphail; Althea D Anderson; Suzanne Maman
Journal:  Cult Health Sex       Date:  2012-03-26

5.  Acceptability and adherence of a candidate microbicide gel among high-risk women in Africa and India.

Authors:  Elizabeth Greene; Georges Batona; Jyoti Hallad; Sethulakshmi Johnson; Stella Neema; Elizabeth E Tolley
Journal:  Cult Health Sex       Date:  2010-10

6.  Re-framing microbicide acceptability: findings from the MDP301 trial.

Authors:  Catherine M Montgomery; Mitzy Gafos; Shelley Lees; Neetha S Morar; Oliver Mweemba; Agnes Ssali; Jonathan Stadler; Robert Pool
Journal:  Cult Health Sex       Date:  2010-08

7.  Context of Acceptability of Topical Microbicides: Sexual Relationships.

Authors:  Helen P Koo; Cynthia Woodsong; Barbara T Dalberth; Meera Viswanathan; Ashley Simons-Rudolph
Journal:  J Soc Issues       Date:  2005-03

8.  Intimate partner violence, relationship power inequity, and incidence of HIV infection in young women in South Africa: a cohort study.

Authors:  Rachel K Jewkes; Kristin Dunkle; Mzikazi Nduna; Nwabisa Shai
Journal:  Lancet       Date:  2010-07-03       Impact factor: 79.321

9.  Gender-based violence, relationship power, and risk of HIV infection in women attending antenatal clinics in South Africa.

Authors:  Kristin L Dunkle; Rachel K Jewkes; Heather C Brown; Glenda E Gray; James A McIntryre; Siobán D Harlow
Journal:  Lancet       Date:  2004-05-01       Impact factor: 79.321

10.  Social Context of Adherence in an Open-Label 1 % Tenofovir Gel Trial: Gender Dynamics and Disclosure in KwaZulu-Natal, South Africa.

Authors:  Kathleen M MacQueen; Sarah Dlamini; Brian Perry; Eunice Okumu; Steve Sortijas; Chitra Singh; Diantha Pillay; Alesha Majors; Sonja Jerome; Sharon Watson; Salim Abdool Karim; Quarraisha Abdool Karim; Leila E Mansoor
Journal:  AIDS Behav       Date:  2016-11
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  6 in total

1.  Couples' Preferences for "2 in 1" Multipurpose Prevention Technologies to Prevent Both HIV and Pregnancy: Results of a Discrete Choice Experiment in Uganda and Zimbabwe.

Authors:  Alexandra M Minnis; Juliane Etima; Petina Musara; Erica N Browne; Prisca Mutero; Doreen Kemigisha; Nyaradzo M Mgodi; Clemensia Nakabiito; Mary Kate Shapley-Quinn; Marie C D Stoner; Miriam Hartmann; Nicole Macagna; Jeanna Piper; Ariane van der Straten
Journal:  AIDS Behav       Date:  2022-06-08

2.  The Power of the Shared Experience: MTN-020/ASPIRE Trial Participants' Descriptions of Peer Influence on Acceptability of and Adherence to the Dapivirine Vaginal Ring for HIV Prevention.

Authors:  Ariana W K Katz; K Naidoo; K Reddy; M Chitukuta; J Nabukeera; S Siva; C Zimba; E T Montgomery
Journal:  AIDS Behav       Date:  2020-08

3.  Impact of Women's Home Environment on Use of the Dapivirine Vaginal Ring for HIV Prevention in Sub-Saharan Africa.

Authors:  Margaret W Gichane; Ariana W K Katz; Kenneth Ngure; Rachel Scheckter; Kubashni Woeber; Krishnaveni Reddy; Thelma Tauya; Chifundo Zimba; Juliane Etima; Nomvuyo Mangxilana; Thesla Palanee-Phillips; Ariane van der Straten
Journal:  AIDS Behav       Date:  2021-05-19

Review 4.  Baseline and time-updated factors in preclinical development of anionic dendrimers as successful anti-HIV-1 vaginal microbicides.

Authors:  Ignacio Rodríguez-Izquierdo; Daniel Sepúlveda-Crespo; Jose María Lasso; Salvador Resino; Ma Ángeles Muñoz-Fernández
Journal:  Wiley Interdiscip Rev Nanomed Nanobiotechnol       Date:  2022-01-12

5.  Acceptability of the Dapivirine Vaginal Ring in Postmenopausal US Women.

Authors:  Mary Kate Shapley-Quinn; Nicole Laborde; Ellen Luecke; Craig Hoesley; Robert A Salata; Sherri Johnson; Annalene Nel; Lydia Soto-Torres; Beatrice A Chen; Ariane van der Straten
Journal:  AIDS Patient Care STDS       Date:  2022-03       Impact factor: 5.944

6.  Acceptability of the Dapivirine Vaginal Ring for HIV-1 Prevention and Association with Adherence in a Phase III Trial.

Authors:  Ashley J Mayo; Erica N Browne; Elizabeth T Montgomery; Kristine Torjesen; Thesla Palanee-Phillips; Nitesha Jeenarain; Linly Seyama; Kubashni Woeber; Ishana Harkoo; Krishnaveni Reddy; Tchangani Tembo; Prisca Mutero; Thelma Tauya; Miria Chitukuta; Brenda Gati Mirembe; Lydia Soto-Torres; Elizabeth R Brown; Jared M Baeten; Ariane van der Straten
Journal:  AIDS Behav       Date:  2021-03-13
  6 in total

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