Literature DB >> 31111096

The association between the APACHE-II scores and age groups for predicting mortality in an intensive care unit: a retrospective study.

Ipek Saadet Edipoglu1, Behiye Dogruel1, Sevda Dizi1, Melis Tosun1, Nahit Çakar1.   

Abstract

BACKGROUND AND AIMS: In this study, we aimed to evaluate whether the age or the APACHE-II score was a better predictor of mortality in each group. The secondary objective was to investigate the factors affecting the mortality in each individual age group.
METHODS: We designed this retrospective study between 2016-2017. Age groups were classified into 3 classes: Patients < 60 years were Group 1, patients between 60-70 years were Group 2, and patients > 70 years were Group 3. We recorded patients' age, ICU indication, demographic data, APACHE-II, ASA, length of hospital stays and mortality.
RESULTS: We analysed 150 patients and reported mortality for 58 patients (38.7%). We did not detect any association between age and mortality for all groups. ASA, length of ICU stays and predicted mortality rate, were significantly higher for exitus patients (p < 0.001). The ROC curve for the APACHE-II score, with a cut-off point of 23, demonstrated 74.14% sensitivity, 60.87% specificity, an area under the curve (AUC) of 67.3%, with 4.5% standard deviation (SD). The ODDS ratio for APACHE-II scores was 4.459 (95% CI: 2.167-9.176). For the adjusted mortality rate, ROC analysis identified a cut-off of 60.8 with 70.69% sensitivity, 52.17% specificity, AUC of 61.2% and 4.6% SD. The ODDS ratio for the adjusted mortality rate was 2.631 (95% CI: 1.309-5.287).
CONCLUSION: We could not demonstrate any correlation between age and mortality. We consider APACHE-II as a valuable scoring system to predict mortality. We do not consider age as a predictor of mortality. Therefore, we do not suggest its use as a sole prognostic marker in ICU patients.

Entities:  

Keywords:  APACHE-II; age; mortality

Year:  2019        PMID: 31111096      PMCID: PMC6502281          DOI: 10.2478/rjaic-2019-0008

Source DB:  PubMed          Journal:  Rom J Anaesth Intensive Care        ISSN: 2392-7518


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