Literature DB >> 31106661

Loss of β-arrestin-2 gene and possible functional consequences on Sezary Syndrome.

Cristina Cristofoletti1, Antonella Bresin1, Elisabetta Caprini1, Giandomenico Russo1, Maria Grazia Narducci1.   

Abstract

Sezary Syndrome is an aggressive T-cell Lymphoma involving blood, skin and lymphonodes Involvement of the CXCR4-SDF1 has been previously shown. We here present evidence also of the involvement of B-arrestin a downstream regulator of CXCR4, that is depleted and downregulated as well as a potential functional role for this depletion.

Entities:  

Keywords:  B-arrestin; CTCL; CXCR4-SDF-1; Copy Number Variation; Leukemia/lymphoma

Mesh：

Substances：

Year:  2019        PMID： 31106661      PMCID： PMC6592223          DOI： 10.1080/15384101.2019.1617007

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


  7 in total

1.  Sezary syndrome and mycosis fungoides arise from distinct T-cell subsets: a biologic rationale for their distinct clinical behaviors.

Authors:  James J Campbell; Rachael A Clark; Rei Watanabe; Thomas S Kupper
Journal:  Blood       Date:  2010-05-18       Impact factor: 22.113

2.  Skin homing of Sézary cells involves SDF-1-CXCR4 signaling and down-regulation of CD26/dipeptidylpeptidase IV.

Authors:  Maria Grazia Narducci; Enrico Scala; Antonella Bresin; Elisabetta Caprini; Maria Cristina Picchio; Daniele Remotti; Gianluca Ragone; Francesca Nasorri; Marina Frontani; Diego Arcelli; Stefano Volinia; Giuseppe Alfonso Lombardo; Giannandrea Baliva; Monica Napolitano; Giandomenico Russo
Journal:  Blood       Date:  2005-10-04       Impact factor: 22.113

3.  Clinical end points and response criteria in mycosis fungoides and Sézary syndrome: a consensus statement of the International Society for Cutaneous Lymphomas, the United States Cutaneous Lymphoma Consortium, and the Cutaneous Lymphoma Task Force of the European Organisation for Research and Treatment of Cancer.

Authors:  Elise A Olsen; Sean Whittaker; Youn H Kim; Madeleine Duvic; H Miles Prince; Stuart R Lessin; Gary S Wood; Rein Willemze; Marie-France Demierre; Nicola Pimpinelli; Maria Grazia Bernengo; Pablo L Ortiz-Romero; Martine Bagot; Teresa Estrach; Joan Guitart; Robert Knobler; José Antonio Sanches; Keiji Iwatsuki; Makoto Sugaya; Reinhard Dummer; Mark Pittelkow; Richard Hoppe; Sareeta Parker; Larisa Geskin; Lauren Pinter-Brown; Michael Girardi; Günter Burg; Annamari Ranki; Maartan Vermeer; Steven Horwitz; Peter Heald; Steve Rosen; Lorenzo Cerroni; Brigette Dreno; Eric C Vonderheid
Journal:  J Clin Oncol       Date:  2011-05-16       Impact factor: 44.544

4.  Combined STAT3 and BCR-ABL1 inhibition induces synthetic lethality in therapy-resistant chronic myeloid leukemia.

Authors:  Anna M Eiring; Brent D G Page; Ira L Kraft; Thomas O'Hare; Patrick T Gunning; Michael W Deininger; Clinton C Mason; Nadeem A Vellore; Diana Resetca; Matthew S Zabriskie; Tian Y Zhang; Jamshid S Khorashad; Alexander J Engar; Kimberly R Reynolds; David J Anderson; Anna Senina; Anthony D Pomicter; Carolynn C Arpin; Shazia Ahmad; William L Heaton; Srinivas K Tantravahi; Aleksandra Todic; Richard Moriggl; Derek J Wilson; Riccardo Baron
Journal:  Leukemia       Date:  2014-08-19       Impact factor: 11.528

5.  Genomic landscape of cutaneous T cell lymphoma.

Authors:  Jaehyuk Choi; Gerald Goh; Trent Walradt; Bok S Hong; Christopher G Bunick; Kan Chen; Robert D Bjornson; Yaakov Maman; Tiffany Wang; Jesse Tordoff; Kacie Carlson; John D Overton; Kristina J Liu; Julia M Lewis; Lesley Devine; Lisa Barbarotta; Francine M Foss; Antonio Subtil; Eric C Vonderheid; Richard L Edelson; David G Schatz; Titus J Boggon; Michael Girardi; Richard P Lifton
Journal:  Nat Genet       Date:  2015-07-20       Impact factor: 38.330

Review 6.  The role and mechanism of β‑arrestins in cancer invasion and metastasis (Review).

Authors:  Qing Song; Qing Ji; Qi Li
Journal:  Int J Mol Med       Date:  2017-11-27       Impact factor: 4.101

7.  Blood and skin-derived Sezary cells: differences in proliferation-index, activation of PI3K/AKT/mTORC1 pathway and its prognostic relevance.

Authors:  Cristina Cristofoletti; Antonella Bresin; Mario Picozza; Maria Cristina Picchio; Francesca Monzo; Mauro Helmer Citterich; Francesca Passarelli; Alessandra Frezzolini; Enrico Scala; Alessandro Monopoli; Maria Cantonetti; Roberto Benucci; Stefania D'Atri; Elisabetta Caprini; Giandomenico Russo; Maria Grazia Narducci
Journal:  Leukemia       Date:  2018-12-05       Impact factor: 11.528
  7 in total
  1 in total

Review 1.  Differential Regulation of GPCRs-Are GRK Expression Levels the Key?

Authors:  Edda S F Matthees; Raphael S Haider; Carsten Hoffmann; Julia Drube
Journal:  Front Cell Dev Biol       Date:  2021-05-24
  1 in total

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