Literature DB >> 31105467

Automated discovery of test statistics using genetic programming.

Jason H Moore1, Randal S Olson1, Yong Chen1, Moshe Sipper1,2.   

Abstract

The process of developing new test statistics is laborious, requiring the manual development and evaluation of mathematical functions that satisfy several theoretical properties. Automating this process, hitherto not done, would greatly accelerate the discovery of much-needed, new test statistics. This automation is a challenging problem because it requires the discovery method to know something about the desirable properties of a good test statistic in addition to having an engine that can develop and explore candidate mathematical solutions with an intuitive representation. In this paper we describe a genetic programming-based system for the automated discovery of new test statistics. Specifically, our system was able to discover test statistics as powerful as the t-test for comparing sample means from two distributions with equal variances.

Entities:  

Keywords:  Genetic Programming; Optimization; Statistics; T-Test

Year:  2018        PMID: 31105467      PMCID: PMC6519943     

Source DB:  PubMed          Journal:  Genet Program Evolvable Mach        ISSN: 1389-2576            Impact factor:   1.714


  5 in total

1.  Extensive variation and low heritability of DNA methylation identified in a twin study.

Authors:  Kristina Gervin; Martin Hammerø; Hanne E Akselsen; Rune Moe; Heidi Nygård; Ingunn Brandt; Håkon K Gjessing; Jennifer R Harris; Dag E Undlien; Robert Lyle
Journal:  Genome Res       Date:  2011-09-26       Impact factor: 9.043

2.  Semiparametric tests for identifying differentially methylated loci with case-control designs using Illumina arrays.

Authors:  Yong Chen; Yang Ning; Chuan Hong; Shuang Wang
Journal:  Genet Epidemiol       Date:  2013-12-03       Impact factor: 2.135

3.  PLMET: A Novel Pseudolikelihood-Based EM Test for Homogeneity in Generalilzed Exponential Tilt Mixture Models.

Authors:  Chuan Hong; Yang Ning; Shuang Wang; Hao Wu; Raymond J Carroll; Yong Chen
Journal:  J Am Stat Assoc       Date:  2017-02-27       Impact factor: 5.033

4.  Increased methylation variation in epigenetic domains across cancer types.

Authors:  Kasper Daniel Hansen; Winston Timp; Héctor Corrada Bravo; Sarven Sabunciyan; Benjamin Langmead; Oliver G McDonald; Bo Wen; Hao Wu; Yun Liu; Dinh Diep; Eirikur Briem; Kun Zhang; Rafael A Irizarry; Andrew P Feinberg
Journal:  Nat Genet       Date:  2011-06-26       Impact factor: 38.330

5.  Investigating the parameter space of evolutionary algorithms.

Authors:  Moshe Sipper; Weixuan Fu; Karuna Ahuja; Jason H Moore
Journal:  BioData Min       Date:  2018-02-17       Impact factor: 2.522

  5 in total

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